Near-infrared fluorescence imaging

Red-HyP-1 is a red dye that can be used for in vivo hypoxia imaging. The maximum emission maximum of Red-HyP-1 is 798 nm.

Indocyanine green (Cardiogreen) is a low toxicic fluorescent agent, is a tricarbocyanine dye,has been widely used in medical diagnostics, such as determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography.

IR-820 (New Indocyanine Green) is a near-infrared dye with improved stability, good color rendering, and excellent fluorescence penetration. It serves as an infrared blood pool contrast agent for detecting and quantifying diseased tissue in live animals, with maximal excitation (Ex) and emission (Em) of 710 and 820 nm, respectively.

Sulfo-Cy5.5 Trifluoroacetate is a kind of cyano dye, which is very suitable for non-invasive in vivo near-infrared imaging, and is suitable for applications that require a low fluorescence background.

FD-1080 is a fluorophore that exhibits both excitation and emission in the NIR-II region, making it suitable for in vivo imaging.

NIR 880 is a fluorescent red dye [1].

FD-1080 free acid, an NIR-II region fluorophore (Ex=1064 nm, Em=1080 nm), facilitates in vivo imaging [1].

CH1055 is a synthetic 970-Da NIR-II fluorophore that is rapidly excreted through the kidneys (~90% within 24 hours) and enables targeted molecular imaging of tumors in vivo when conjugated with anti-EGFR Affibody [1].

IR-1048 (S01448) is both a dye and a photothermal agent, and it can be utilized for tumor diagnosis research [1] [1].

Nile Blue Methacrylamide, a Nile Blue-based nanosized pH sensor, enables simultaneous far-red and near-infrared live bioimaging [1].

Fluorescent polyamine probe-1 (compound 15) is a linear polyamine probe characterized by its high uptake efficiency. It is employed in studying the transport systems into cancer cells [1].

Fluorescent NIR 885 is a dye molecule that can be used in life science related research. The CAS number of Fluorescent NIR 885 is 177194-56-8.

ICG-carboxylic acid is a fluorescent probe in the near-infrared (NIR) range. It is derived from indocyanine green (ICG), a commonly used fluorescent dye in medical diagnostics. ICG exhibits a peak absorption at 800 nm, allowing it to efficiently absorb energy from near-infrared lasers and release heat within the dyed tissue.

Disulfo-ICG carboxylic acid, a derivative of ICG (Indocyanine Green), is a NIR fluorescent dye [1].

Gd-NMC-3, a bimodal imaging probe, exhibits high resolution and sensitivity for tumor imaging with favorable biocompatibility, demonstrating significant potential for application in near-infrared fluorescence/magnetic resonance (NIRF/MR) imaging [1].

Near-IR fluorescent probe-1 represents a versatile dye employed extensively across various scientific and industrial sectors. As vital tools in biological experiments, dyes facilitate the observation and analysis of cell structures, tracking of biomolecules, evaluation of cell functions, differentiation of cell types, detection of biomolecules, tissue pathology studies, and microorganism monitoring. Their utility spans from fundamental research to a broad spectrum of clinical diagnostics. Additionally, dyes find application in classic industries like textile dyeing and are progressively being utilized in innovative areas including functional textile processing, food coloring, and dye-sensitized solar cells.

Fluorescent red 610 is a dye characterized by an excitation peak at 590 nm and an emission peak at 610 nm [1].

HITCI, a commercially available cationic indocarbocyanine dye, is typically utilized as a laser dye within the near-infrared (NIR) [1] spectrum.

IR-1061 is a near-infrared fluorescent organic dye utilized for in vivo OTN-NIR imaging [1].

IR 813 perchlorate, a near-infrared (NIR) fluorescent dye (Ex=815 nm, Em=840 nm), is utilized for visualizing regional lymph nodes in mice [1].

IR-797 chloride, a near-infrared (NIR) dye, exhibits absorption maxima near 700 nm and demonstrates aggregation-induced-emission (AIE) properties. Additionally, IR-797 shows cytotoxic [1] [2].

IR-251 is a mitochondrion-targeting near-infrared (NIR) fluorescent probe that selectively accumulates in tumor cell mitochondria through organic anion transporting polypeptides (OATPs), leading to mitochondrial dysfunction. By impeding peroxisome proliferator-activated receptor gamma (PPARγ), IR-251 promotes reactive oxygen species (ROS) overproduction, consequently inhibiting the β-catenin signaling pathway as well as associated cell cycle and metastasis proteins. This mechanism contributes to the compound's ability to suppress tumor growth and metastasis [1].