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Curcuma

  • β-Elemene
    T13476515-13-9
    β-Elemene (Levo-β-elemene) is a natural product isolated from Curcuma wenyujin, with an antitumor activity and induce cell apoptosis.
    • $68
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    TargetMol | Citations Cited
  • Hexahydrocurcumin
    TQ028836062-05-2
    Hexahydrocurcumin is a selective, orally active COX-2 inhibitor and inactive against COX-1.
    • $122
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  • Curcumenol
    T366919431-84-6
    Curcumenol ((+)-Curcumenol), one of the major components of Zedoary turmeric oil, is an antibiotic drug which has anti-Y, anti-inflammation activity. Curcumenol may be safely used without inducing metabolic drug-drug interaction through P450 inhibition.
    • $55
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  • Dimethylcurcumin
    TQ021452328-98-0
    Dimethylcurcumin (ASC-J9) (ASC-J9) is an androgen receptor degradation enhancer. It effectively suppresses castration-resistant prostate cancer cell proliferation and invasion.
    • $130
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  • Bisdemethoxycurcumin
    TL000724939-16-0
    Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by macrophages (optimal stimulation at 100 nM BDMC) [1]. More stable than curcumin in physiological media, BDMC suppresses proliferation of cancer cells [2]. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits LPS induction of iNOS expression [3].
    • $31
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  • Octahydrocurcumin
    T3S169236062-07-4
    Octahydrocurcumin has antioxidant and and anti-inflammatory activities, it can inhibit the lipopolysaccharide (LPS)-induced inflammatory response via the mechanism of inhibiting NF-kB translocation to the nucleus. Octahydrocurcumin exhibits potent cytotoxic effect (IC50 =19.46 ug mL) and shows high antimicrobial activity.
    • $42
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  • Curdione
    T341113657-68-6
    Curdione ((+)-Curdione) inhibits CYP3A4 activity and the production of prostaglandin E2. Curdione inhibits proliferation of MCF-7 cells by inducing apoptosis. Curdione may be a candidate for anti-inflammatory and Y chemopreventive agents.
    • $43
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  • Kaempferol 3,7,4'-trimethyl ether
    TN181715486-34-7
    Kaempferol 3,7,4'-trimethyl ether (Kaempferol 3,7,4'-trimethylether) demonstrates selective cytotoxic activities against nine tested cancer cell lines.
    • $73
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  • Tetramethylcurcumin
    TN226952328-97-9In house
    Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and exhibit synergy with the anti-cancer drug doxorubicin against breast cancer cells.
    • $39
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  • Furanodienone
    T4S054424268-41-5
    1. Furanodienone has effects on MCF-7 cells are mediated, at least in part, by inhibiting ERα signaling. 2. Furanodienone inhibits EGFR/HER2 signaling pathway in BT474 and SKBR3 cells, the effect is specifically dependent on the expression of HER2 but not EGFR .
    • $54
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  • Furanodiene
    TN165119912-61-9
    Furanodiene has anti-inflammatory and antioxidant activities, it is active against gram-positive bacteria and Candida albicans.
    • $52
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  • Curzerene
    T3S054117910-09-7
    Curzerene, a sesquiterpene compound derived from the rhizome of Curculigo orchioides Gaertn, possesses potent anti-cancer properties. It is known to induce apoptosis in cells[1] and also suppress the expression of glutathione S-transferase A1 (GSTA1) mRNA and protein.
    • $44
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  • Ayanin
    TN1416572-32-7
    Ayanin has vasorelaxant activity, it also may have the potential for use in treating allergic asthma.The IC(50) value of Ayanin (quercetin-3,7,4'-O-trimethylether) is 2.2microM for inhibiting interleukin (IL)-4 production from purified basophils.
    • $176
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  • Kaempferol 5,7,4'-trimethyl ether
    TN43711098-92-6
    Kaempferol 5,7,4'-trimethyl ether is a natural product for research related to life sciences. The catalog number is TN4371 and the CAS number is 1098-92-6.
    • $290
    5 days
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  • Diarylcomosol III
    TN38421452487-93-2
    Diarylcomosol III shows inhibitory effects on melanogenesis in B16 melanoma cells, it is a promising therapeutic agent for the treatment of skin disorders.
    • $660
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  • 7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB)
    TN321779559-60-7
    7-(4-hydroxy-3-methoxyphenyl)-1-phenylhept-4-en-3-one (DPHB) is a natural product for research related to life sciences. The catalog number is TN3217 and the CAS number is 79559-60-7.
    • $540
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  • Germacrone 4,5-epoxide
    TN413092691-35-5
    (4S,5S)-(+)-Germacrone-4,5-epoxide inhibits certain subtypes of cytochrome P450 (CYP).
    • $540
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  • 7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one
    TN3218100667-52-5
    7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity and cell survival, and may provide new insights on drug discovery of Alzheimer's disease (AD).
    • $540
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  • Curcumaromin B
    TN56651810034-39-9
    Curcumaromin B is a natural product from Curcuma aromatica Salisb.
    • $860
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  • Aerugidiol
    TN5400116425-35-5
    Aerugidiol inhibits protein tyrosine phosphatase 1B (PTP1B).
      7-10 days
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    • 5'-Methoxyhexahydrocurcumin
      TN5656138870-96-9
      5 -Methoxyhexahydrocurcumin is a natural product for research related to life sciences. The catalog number is TN5656 and the CAS number is 138870-96-9.
      • $660
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    • 1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one
      TN5661207792-17-4
      1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one exhibits strong inhibition of collagen-induced, arachidonic acid-induced, and adenosine diphosphate-induced platelet aggregation in human whole blood.
      • $660
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    • Bisacurone C
      TN3516127214-86-2
      Bisacurone C is a natural product from Curcuma longa.
      • $317
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    • 3,5-Dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)heptane
      TN2896408324-00-5
      (3R,5R)-3,5-dihydroxy-1-(3,4-dihydroxyphenyl)-7-(4-hydroxyphenyl)-heptane may have anti-adipogenic activity.
      • $1,870
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    • 5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone (DHPA)
      TN311879559-61-8
      5-Hydroxy-7-(4'-hydroxy-3'-methoxyphenyl)-1-phenyl-3-heptanone (DHPA) is a pancreatic lipase inhibitor, it shows antihyperlipidemic activity.
      • $1,398
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    • Curcumenone
      TN1537100347-96-4
      Curcumenone may have protective effect on drunkenness, through increasing liver alcohol dehydrogenase activity.
      • $540
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    • Selina-4(15),7(11)-dien-8-one
      TN346754707-47-0
      Selina-4(15),7(11)-dien-8-one is a natural product for research related to life sciences. The catalog number is TN3467 and the CAS number is 54707-47-0.
      • $313
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    • Curcumaromin A
      TN56601810034-38-8
      Curcumaromin A is a natural product from Curcuma aromatica Salisb.
      • $860
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    • Curcolonol
      TN3731217817-09-9
      Curcolonol is a natural product of Curcuma, Zingiberaceae. The catalog number is TN3731 and the CAS number is 217817-09-9. Curcolonol can be used as a reference standard.
      • $760
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    • Dehydrochromolaenin
      TN379820013-76-7
      Dehydrochromolaenin is a natural product for research related to life sciences. The catalog number is TN3798 and the CAS number is 20013-76-7.
      • $520
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    • Procurcumenol
      TN210221698-40-8
      Procurcumenol is an inhibitor of Nitric Oxide. Procurcumenol and epicurcumenol have inhibitory effects on release of tumor necrosis factor-a (TNF-a).
      • $540
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    • 3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane
      TN2897408324-01-6
      3,5-Dihydroxy-1,7-bis(3,4-dihydroxyphenyl)heptane is a natural product for research related to life sciences. The catalog number is TN2897 and the CAS number is 408324-01-6.
      • $252
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    • omega-Benzoyl oxyphloracetophenone
      TN470965982-77-6
      omega-Benzoyl oxyphloracetophenone is a natural product for research related to life sciences. The catalog number is TN4709 and the CAS number is 65982-77-6.
      • $110
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    • Isocurcumenol
      T5S054324063-71-6
      1. Isocurcumenol inhibits 5α-reductase which converts testosterone to dihydrotestosterone (DHT).
      • $79
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    • Curzerenone
      TN153820493-56-5
      Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52).
      • $1,210
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    • (3R,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol
      TN6486232261-31-3
      (3R,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol is a natural product for research related to life sciences. The catalog number is TN6486 and the CAS number is 232261-31-3.
      • $620
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    • (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol
      TN576187095-75-8
      (3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol has anti-oomycete potential.
      • $620
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    • Curcumaromin C
      TN37331810034-40-2
      Curcumaromin C is a natural product from Curcuma aromatica Salisb.
      • $750
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    • Zedoarondiol
      TN232798644-24-7
      Zedoarondiol has anti-inflammatory activity, inhibits iNOS, COX-2, and pro-inflammatory cytokine expressions by suppressing the phosphorylations of IKK and MAPKs, and by subsequently inactivating the NF-kappaB pathway.
        7-10 days
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      • 4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one
        TN2994170380-68-4
        4-(6-Methyl-4-oxohept-5-en-2-yl)cyclohex-2-en-1-one is a natural product for research related to life sciences. The catalog number is TN2994 and the CAS number is 170380-68-4.
        • $334
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      • 5-Hydroxy-1-(4-hydroxyphenyl)-7-phenyl-3-heptanone (AO 2210)
        TN3114105955-04-2
        (±)-5-hydroxyl-1-(4'-hydroxyphenyl)-7-phenyl-3-heptanone have digestibility inhibition in vitro in cow rumen fluid.
        • $590
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      • Cyclocurcumin
        TN3741153127-42-5
        Cyclocurcumin, a curcumin derivative, exhibits anticancer, anti-inflammatory, and immune-modulating abilities and is a potential compound for the treatment of rheumatoid arthritis as predicted by the MM-PBSA method. It may have a therapeutic potential as
        • $288
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      • 4-Epi-curcumenol
        TN3025350602-21-0
        4-Epi-curcumenol is a natural product of Curcuma, Zingiberaceae. The catalog number is TN3025 and the CAS number is 350602-21-0. 4-Epi-curcumenol can be used as a reference standard.
        • $730
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      • Voleneol
        TN524870389-88-7
        1β,6α-Dihydroxyeudesm-4(15)-ene (Voleneol,DE) can attenuate the lipopolysaccharide (LPS)-induced inflammation in BV2 microglial cells, it also can dose-dependently suppress the protein expression of inducible nitric oxide synthase (iNOS) and cyclooxygenas
        • $540
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      • 3,4-Dihydroxybisabola-1,10-diene
        TN2880129673-87-6
        3,4-Dihydroxybisabola-1,10-diene is a natural product for research related to life sciences. The catalog number is TN2880 and the CAS number is 129673-87-6.
        • $710
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      • Zederone
        TN52787727-79-9
        Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that cause the oxidative stress and liver cell injuries.
        • $423
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      • 2-Methoxy-5-acetoxy-fruranogermacr-1(10)-en-6-one
        TN12141809980-25-3
        2-Methoxy-5-acetoxy-furanogermacr-1(10)-en-6-one is a natural product
        • $300
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      • Turmeronol A
        TN5196131651-37-1
        Turmeronol A and turmeronol B are inhibitors of soybean lipoxygenase, they inhibited soybean lipoxygenase at the IC50 values of 16 uM and 9 uM, respectively.
        • $550
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      • 1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)hept-6-en-3-ol
        TN24711206788-61-5
        1-(3,4-Dihydroxyphenyl)-7-(4-hydroxyphenyl)hept-6-en-3-ol is a natural product used in life sciences research. The catalog number is TN2471 and the CAS number is 1206788-61-5.
        • $2,289
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      • Neoprocurcumenol
        TN4641102130-91-6
        Neoprocurcumenol exerts significant toxicity on mosquito larvae.
        • $510
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