Cepharanthine (NSC-623442) is a natural alkaloid that inhibits TNF-α-mediated NFκB stimulation, plasma membrane lipid peroxidation, and platelet aggregation, as well as cytokine production. Cepharanthine exhibits anti-inflammatory, antioxidant, and antitumor activities.
Tetrandrine (Sinomenine A) is a naturally occurring biphenylisoquinoline alkaloid, a calcium channel inhibitor. Tetrandrine inhibits voltage-gated calcium channels (ICa) and Ca2+-activated potassium channels.
1. Crebanine iv 5mg/kg can eonvert BaCl_2-induced arrhythmia into sinus rhythm in rats, and can significantly increase the tolerant dose of aconitine to produce ventrieular fibrillation(VF) and cardiac arrest (CA) in rata. 2. Crebanine can also decrease t
16-Oxoprometaphanine is a natural product of Stephania, Menispermaceae. The catalog number is TN6023 and the CAS number is 58738-31-1. 16-Oxoprometaphanine can be used as a reference standard.
Oblongine chloride may have potential haemodynamic effects, it can cause a dose-dependent reduction of systolic and diastolic blood pressure, and that these effects are not mediated by α²-adrenergic receptor stimulation.
Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng/ml.
Dihydroepistephamiersine 6-acetate is a natural product for research related to life sciences. The catalog number is TN3850 and the CAS number is 57361-74-7.
Dicentrine, a selective α±(1)-adrenoceptor antagonist with potent antiarrhythmic and antihypertensive activities, it also has antinociception in different models of chemical pain.
Epistephamiersine is a natural product of Stephania, Menispermaceae. The catalog number is TN6018 and the CAS number is 52389-15-8. Epistephamiersine can be used as a reference standard.
11-Hydroxyjasmonic acid is a natural product of Stephania, Menispermaceae. The catalog number is TN2585 and the CAS number is 140447-14-9. 11-Hydroxyjasmonic acid can be used as a reference standard.
L-Stepholidine, which has dual actions on dopamine D1 and D2 receptors, attenuates heroin self-administration and cue-induced reinstatement. It also elicits anti-dyskinesia effects.