Microhelenin C has significant antileukemic activity.

Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling pathways. Arnicolide D inhibits Nasopharyngeal carcinoma (NPC) cell viability in a concentration- and time-dependent manner. Arnicolide D exerts strong cytotoxic activity on the human colon carcinoma HT-29 cell line.

Arnicolide C (Isobutyroylplenolin) is a sesquiterpene lactone metabolite naturally found in Centipeda minima and Arnica montana. Arnicolide C is reported to possess diverse biological activities, including anti-inflammatory, antiallergy, antitumor, anticancer, and antiprotozoal properties, making it a multifunctional natural product.

Minimolide L is a sesquiterpene discovered in Centipeda minima, suitable for biochemical experiments and drug synthesis research.

6-O-Senesioyl plenolin is a sesquiterpene lactone discovered in Centipeda minima, exhibiting significant anti-allergic activity in passive cutaneous anaphylaxis (PCA) tests.