Targeted Drug Delivery System

trans-Hex-2-enoic acid is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

113-N16B is an ionizable cationic lipid suitable for synthesizing lipid nanoparticles, capable of delivering mRNA to endothelial cells in the lungs.

1-Tricosanol is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Cholesta-3,5-diene is an inflammation modulator targeting immune cells (such as neutrophils), facilitating wound healing by promoting neutrophil chemotaxis and fibroblast migration. It enhances immune cell recruitment and extracellular matrix deposition by activating chemokine receptor-mediated signaling pathways (such as PI3K Akt). Cholesta-3,5-diene can be applied topically for wound repair, showing potential therapeutic value in chronic ulcers or skin injuries.

5β,6β-Epoxycholestanol is an oxidative metabolite of cholesterol produced through radical and non-radical oxidation at the 5,6-double bond. It induces the release of lactate dehydrogenase (LDH) and apoptosis in differentiated macrophage U937 cells. This compound has been identified in human fatty streaks and advanced atherosclerotic lesions but is absent in normal aortic tissue.

16:0 DAP is a cationic lipid that can serve as a drug delivery vector.

IAJD249 is an ionizable lipid. This type of lipid is crucial for endosomal escape and the delivery of RNA into the cytosol, due to its ability to form unstable non-bilayer structures at acidic pH. IAJD249 is also utilized in the preparation of liposomes.

α-D-Glucopyranose, 2,3,4,6-tetraacetate is a biochemical reagent.

N-Benzyloxycarbonyl-2-phosphonoglycine trimethyl ester is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

1,2-Dilaurin is a diacylglycerol compound with lauric acid at the sn-1 and sn-2 positions. It is utilized as an internal standard for quantifying diacylglycerols in desheathed rat sciatic nerves. Monomolecular films containing 1,2-dilauroyl-rac-glycerol serve as substrates to assess surface pressure and the effects of procolipase and colipase on porcine pancreatic lipase activity.

AlkyneCholesterol is a modified lipid and serves as a click chemistry reagent containing an alkyne group. In the presence of a copper (Cu) catalyst, the terminal alkyne can engage in highly specific ligation reactions with azide-containing reagents. AlkyneCholesterol is useful for tracking cellular cholesterol metabolism and localization.

18:0-18:2 PE is a lipid used in drug delivery, primarily composed of unsaturated fatty acids. It is considered a key precursor of important odors (IOs) in Eriocheir sinensis.

L16 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA cytosolic delivery. L16 can be utilized in liposome preparation.

LNP Lipid-3 is an ionizable lipid utilized in the synthesis of lipid nanoparticles, originating from patent WO2021113777A1.

DL-Dipalmitoylphosphatidylcholine (DL-DPPC) is a biochemical reagent.

A12-Iso5-4DC19 is an ionizable cationic lipid that enhances mRNA delivery and is utilized in research concerning RNA vaccines.

trans-11-Eicosenoic acid is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Ethyl stearate is an ester compound synthesized from ethanol and stearic acid. It is commonly used as a flavoring agent in various foods, such as baked goods, beverages, and desserts. Additionally, ethyl stearate serves as a fragrance component in the production of perfumes, colognes, and personal care products. It also finds industrial applications, including the manufacture of lubricants and plasticizers.

Undecylenate sodium is an organic compound that belongs to the class of carboxylates. It is formed through the reaction of undecylenic acid with sodium hydroxide. Undecylenate sodium has numerous applications in the cosmetics and personal care industry, notably serving as an antifungal agent in products such as creams, lotions, and shampoos. Additionally, it functions as a preservative in various formulations.

1O14 is an ionizable lipid. Its ability to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA cytosolic delivery. 1O14 is applicable in the preparation of liposomes.

Lipid 6 is an ionizable amino lipid (amino lipid) used for the synthesis of lipid nanoparticles (LNPs).

Lipid 1 is an ionizable aminolipid used in the synthesis of lipid nanoparticles.

IAJD93 is an ionizable lipid. Its ability to form unstable non-bilayer structures at acidic pH is crucial for endosomal escape and RNA delivery into the cytosol. IAJD93 can be utilized in the preparation of liposomes.

Behenamide is derived from fatty acids found in plant oils such as canola and can be synthesized through various processes. Known for its unique properties, behenamide serves as a slip agent, lubricant, and mold release agent in industrial applications like plastic processing, paper coatings, and adhesives manufacturing. It is also used in personal care products, including cosmetics and hair care, functioning as a thickener and emollient to enhance formulation consistency and texture.