Cell Research Reagents

Cytochrome C, a protein that belongs to class 1 of the c-type cytochrome family, exerts different functions depending on its cellular localization and the conditions in which it operates.

L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals. L-Glutathione reduced is a cofactor for certain enzymes and is involved in the rearrangement of protein disulfide bonds and the reduction of peroxides.

Methoxy-PMS (1-Methoxyphenazine methosulfate) is stable electron-transport mediator between NAD(P)H and tetrazolium dyes, can induce active oxygen formation.

Evans blue (C.I. 23860) is an azo dye, inhibits L-glutamate uptake via the membrane-bound excitatory amino acid transporter (EAAT).

ON-01910 is a non-ATP-competitive PLK1 inhibitor(IC50 of 9 nM, in a cell-free assay). It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Rigosertib inhibits PI3K/Akt pathway and activates oxidative stress signals. Rigosertib induces apoptosis in various cancer cells.It is a synthetic benzyl styryl sulfone analogue with potential antineoplastic activity.

3-Indoleacetic acid (indolylacetic acid) (IAA) is the most common plant hormone of the auxin class and it regulates various aspects of plant growth and development.

Lysophosphatidylcholines (Lyso-Lecithins (egg)) are orally active lipids that induce cell damage and apoptosis, and induce demyelination. Lysophosphatidylcholines play a role in mediating inflammation, fibrosis, and cancer, and can be used to study atherosclerosis.

ISRIB is a potent and selective PERK inhibitor.

Imidazole is a planar 5-membered ring and a highly polar compound. It has been used extensively as a corrosion inhibitor. Imidazole is incorporated into many important biological molecules.

Cobaltic Protoporphyrin IX chloride (CoPP) is a potent heme oxygenase 1 (HO-1) inducer with antiviral activity that inhibits influenza A virus (IAV) infection by inducing a type I IFN response. mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activities.

Diatrizoate meglumine (Renocal) is the meglumine salt of diatrizoate, it is an organic, iodinated, radiopaque X-ray contrast medium used in diagnostic radiography.

3-Amino-1,2,4-triazole (Trapidil impurity B) is an inhibitor of catalase, capable of inducing the compensatory mechanism for hydrogen peroxide detoxification. This mechanism involves increasing the activities of glutathione peroxidase and glutathione reductase.

Palmitic acid sodium (Sodium palmitate) is a type of saturated fatty acid that is formed in fatty acid synthesis.Palmitic acid sodium promotes adipogenesis and cellular lipoatrophy in a variety of cell lines.

Magenta Phosphate (5-Bromo-6-chloro-3-indolyl phosphate p-toluidine) enables the visualization of alkaline phosphatase activity through generation of an insoluble magenta-colored precipitate. When used in combination with nitro blue tetrazolium, this system permits visual interpretation of experimental results.

Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.

Hexacosanol activates AMPK and hepatic autophagy and inhibits SREBP2, resulting in hypocholesterolemic activities and improvement of hepatic steatosis.

3β,5α,6β-Trihydroxycholestane is a cholesterol metabolite found mainly in animal fats and can modulate SMO activity.3β,5α,6β-Trihydroxycholestane can be used as a biomarker for schizophrenia.

1-Dodecylimidazole (N-Dodecylimidazole) is a chemical compound that acts as a cytotoxic agent and lysosomotropic detergent, inducing cell death through acid-dependent lysosomal accumulation, disrupting the lysosomal membrane, and releasing cysteine proteases into the cytoplasm. It also exhibits hypocholesterolemic and broad-spectrum antifungal activities.

Pipecolic acid (2-Piperidinecarboxylic acid), a metabolite of lysine found in human physiological fluids such as urine, plasma and CSF, is an important regulator of immunity in plants and humans alike.

1-Naphthaleneacetic acid (Transplantone) , is widely used in agriculture for various purposes. It is a synthetic plant hormone in the auxin family and is an ingredient in many commercial plant rooting horticultural products.

Lithocholic acid 3-sulfate disodium (Sulfolithocholic acid disodium) acts as a RORgammat ligand and inhibits Th17 cell differentiation.Lithocholic acid 3-sulfate disodium is a sulfated product of lithocholic acid (LCA) and induces a decrease in arterial blood pressure. Lithocholic acid 3-sulfate disodium is a sulfated product of lithocholic acid (LCA) that induces cellular damage.

2-Acetylthiophene (1-(2-Thienyl)ethanone) is a RIFM fragrance.

1, 3-Diphenylurea is involved with Epoxide hydrolase activity.

Sodium caseinates are proteins found in milk that induce proliferation and activation of granulocytes, and can induce granulopoiesis in mice.Sodium caseinates are used as thickeners and emulsifiers and are commonly used in the food industry.