TN2895 |
3,5-Dicaffeoyl-epi-quinic acid
|
879305-14-3
|
98%
|
|
3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases.
|
T4S1057 |
Tripdiolide
|
38647-10-8
|
98%
|
|
Tripdiolide has cytotoxic, and anti-rheumatic activities, it suppresses pro-inflammatory gene expression, may be effective therapy for lupus nephritis.
|
TN3541 |
Broussonin E
|
90902-21-9
|
98%
|
|
Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathwa...
|
TN3655 |
Cimiside E
|
154822-57-8
|
98%
|
|
Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-α-induced expression of VCAM-1 at least by upregulation of PPAR-γ, and signals for ERK1/2,...
|
TN4013 |
Esculentic acid
|
103974-74-9
|
98%
|
|
Esculentic acid has anti-inflammatory effect, it has protective effects against LPS-induced endotoxic shock may be mediated, at least in part, by regulation the ...
|
T10350 |
Apremilast-d5
|
1258597-47-5
|
98%
|
|
Apremilast D5 (CC-10004 D5) is a deuterium-labeled Apremilast. Apremilast is an orally available inhibitor of PDE-4 (IC50: 74 nM). Apremilast inhibits TNF-α rele...
|
TN3806 |
Dehydroglyasperin C
|
199331-35-6
|
98%
|
|
Dehydroglyasperin C is a potent NAD(P)H:oxidoquinone reductase (NQO1) and phase 2 enzyme inducer. Dehydroglyasperin C possesses potent antioxidant, cancer chemop...
|
TN4418 |
Lasiodiplodin
|
32885-81-7
|
98%
|
|
Lasiodiplodin may have potential anti-inflammatory activity, it shows moderate suppression effects on induced NO production. Lasiodiplodin inhibits electron tran...
|
TN4635 |
Neoechinulin A
|
51551-29-2
|
98%
|
|
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the ...
|
T6591 |
Nodinitib-1
|
799264-47-4
|
99.98%
|
|
Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 μM.
|
T8845 |
UTL-5g
|
646530-37-2
|
99.97%
|
|
UTL-5g (3-Isoxazolecarboxamide, N-(2,4-dichlorophenyl)-5-methyl-) is a novel potential chemoprotective agent, TNF-α inhibitor that reduces cisplatin-induced side...
|
T3332 |
Isosteviol
|
27975-19-5
|
99.97%
|
|
Isosteviol ((-)-Isosteviol), a common natural sweetener, belongs to tetracyclic diterpene glycosides. The pharmacology researches have suggested that stevioside ...
|
T2205 |
Acefylline
|
652-37-9
|
99.95%
|
|
Acefylline (Theophylline-7-acetic acid), a stimulant drug of the xanthine chemical class, acts as an adenosine receptor antagonist. It is combined with diphenhyd...
|
T9057 |
Norbergenin
|
79595-97-4
|
99.93%
|
|
Norbergenin is a chemical compound. It is the O-demethylated derivative of bergenin. It can be isolated from rhizomes of Bergenia stracheyi.
|
TN1933 |
Mitraphylline
|
509-80-8
|
99.93%
|
|
Mitraphylline has antiproliferative effects on human glioma and neuroblastoma cell lines. It also has anti-inflammatory activity, it inhibits lipopolysaccharide-...
|
T6S2099 |
Geraniin
|
60976-49-0
|
99.92%
|
|
1. Geraniin has a protective effect against OVX-induced rat osteoporosis. 2. Geraniin has cytotoxic activity towards cancer cells in vitro and in vivo. 3. Gerani...
|
T2S0843 |
Negletein
|
29550-13-8
|
99.92%
|
|
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotecta...
|
T4403 |
AX-024 hydrochloride
|
1704801-24-0
|
99.9%
|
|
AX-024 hydrochloride (AX-024 HCl) is an cytokine release inhibitor which can strongly inhibit the production of interleukin-6 (IL-6), tumor necrosis factor-α (TN...
|
T4450 |
GIBH-130
|
1252608-59-5
|
99.86%
|
|
GIBH-130 markedly inhibits the IL-1β secretion by activated microglia (IC50: 3.4 nM). GIBH-130 is an effective inhibitor of neuroinflammation.
|
T6204 |
QNZ
|
545380-34-5
|
99.86%
|
|
QNZ (EVP4593) (EVP4593) is an effective inhibitor of NF-κB activation and TNF-α production. The IC50 of QNZ for NF-κB and TNF-α is11 nM and 7 nM, respectively.
|