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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Signaling Pathways | Target | TargetMol
Cat. No. Product name CAS No. Purity Chemical Structure
T0916 Butamben 94-25-7 99.61%
Butamben
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
T12655 (Rac)-AMG8379 1641574-26-6 99.6%
(Rac)-AMG8379
(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.
T0460 Pramocaine hydrochloride 637-58-1 99.57%
Pramocaine hydrochloride
Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.
T0386 Ropivacaine hydrochloride 98717-15-8 99.55%
Ropivacaine hydrochloride
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity....
T6234 Ambroxol hydrochloride 23828-92-4 99.55%
Ambroxol hydrochloride
Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is ...
T22675 Co 102862 181144-66-1 99.54%
Co 102862
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.
T1308 Orphenadrine hydrochloride 341-69-5 99.54%
Orphenadrine hydrochloride
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
T80626 VGSCs-IN-1 1204296-79-6 99.50%
VGSCs-IN-1
VGSCs-IN-1 is a potent VGSC inhibitor, a 2-piperazine analog of Riluzole that exhibits good blocking activity on Nav1.4.VGSCs-IN-1 can be used to study cellular ...
T7064 Valproic Acid 99-66-1 99.49%
Valproic Acid
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be u...
T28686 SB-237376 HCl 179258-62-9 99.49%
SB-237376 HCl
SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias.
T1389 Dyclonine hydrochloride 536-43-6 99.49%
Dyclonine hydrochloride
Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .
T4490 PF-01247324 875051-72-2 99.47%
PF-01247324
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
T9647 GX 201 1788071-27-1 99.46%
GX 201
GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.
T0364L Dibucaine hydrochloride 61-12-1 99.45%
Dibucaine hydrochloride
Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.
T16897 SM-6586 103898-38-0 99.43%
SM-6586
SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular ...
T7502L PF 05089771 1235403-62-9 99.42%
PF 05089771
PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that...
T0862 Diphenidol hydrochloride 3254-89-5 99.42%
Diphenidol hydrochloride
Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.
T28686L SB-237376 179258-59-4 99.41%
SB-237376
SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.
T79835 Aneratrigine hydrochloride 2097163-75-0 99.39%
Aneratrigine hydrochloride
Aneratrigine hydrochloride is a sodium channel protein type 9 subunit blocker that may be used for the prevention or treatment of sodium channel blocker-related ...
T2342 Raxatrigine 934240-30-9 99.39%
Raxatrigine
Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
Butamben
T0916
Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.
(Rac)-AMG8379
T12655
(Rac)-AMG8379 ((Rac)-AMG8380) is a racemate of AMG8379 which is an orally active and selective sulfonamide NaV1.7 antagonist.
Pramocaine hydrochloride
T0460
Pramocaine hydrochloride (Pramoxine HCl), a topical anesthetic, is served as an antipruritic.
Ropivacaine hydrochloride
T0386
Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activity....
Ambroxol hydrochloride
T6234
Ambroxol hydrochloride (Mucosolvan) is a metabolite of BROMHEXINE that stimulates mucociliary action and clears the air passages in the respiratory tract. It is ...
Co 102862
T22675
Co 102862 is a voltage-gated sodium channel blocker. Co 102862 can be used for anticonvulsant studies.
Orphenadrine hydrochloride
T1308
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
VGSCs-IN-1
T80626
VGSCs-IN-1 is a potent VGSC inhibitor, a 2-piperazine analog of Riluzole that exhibits good blocking activity on Nav1.4.VGSCs-IN-1 can be used to study cellular ...
Valproic Acid
T7064
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be u...
SB-237376 HCl
T28686
SB-237376 HCl (SB-237376 hydrochloride) is a calcium and potassium channel antagonist used in the treatment of cardiac arrhythmias.
Dyclonine hydrochloride
T1389
Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect .
PF-01247324
T4490
PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).
GX 201
T9647
GX 201 is a selective NaV1.7 inhibitor, IC50 of < 3.2 nM for hNaV1.7.
Dibucaine hydrochloride
T0364L
Dibucaine hydrochloride (Cinchocaine hydrochloride), a long-acting local amide anestheticsis, is usually used for surface anesthesia.
SM-6586
T16897
SM-6586 is a potent calcium channel antagonist with inhibitory effects on Na+/H+ and Na+/Ca2+ exchange channels, and can be used in the study of cerebrovascular ...
PF 05089771
T7502L
PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV. It shows a slow onset of the block that...
Diphenidol hydrochloride
T0862
Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.
SB-237376
T28686L
SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.
Aneratrigine hydrochloride
T79835
Aneratrigine hydrochloride is a sodium channel protein type 9 subunit blocker that may be used for the prevention or treatment of sodium channel blocker-related ...
Raxatrigine
T2342
Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
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TargetMol