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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.
Cat. No. Product name CAS No. Purity Chemical Structure
TQ0157 EIPA 1154-25-2 98.52%
EIPA (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
T3956 Sodium ionophore III 81686-22-8 98.54%
Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
T0024 Primidone 125-33-7 98.68%
Primidone is an anticonvulsant of the pyrimidinedione class.
T0275 Meticrane 1084-65-7 98.74%
Meticrane is a sulphonamide-derivative with thiazide-like diuretic activity.
T0946 Mepivacaine hydrochloride 1722-62-9 98.76%
Mepivacaine Hydrochloride is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.
T1334 Hydroquinidine 1435-55-8 98.9%
Dihydroquinidine is an organic compound, used as an antiarrhythmic agent.
T1033 Monensin sodium salt 22373-78-0 98.9%
Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt causes a marked enlargement of the MVBs and regulates exoso...
T15207 Eleclazine hydrochloride 1448754-43-5 98.95%
Eleclazine hydrochloride is a novel inhibitor of late Na+ current (IC50: 0.7 uM).
T3402 20(S)-Ginsenoside Rg3 14197-60-5 98.99%
Ginsenoside Rg3 possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the prol...
T7064 Valproic Acid 99-66-1 99%
Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various mol...
T0802 Procaine hydrochloride 51-05-8 99%
Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds ...
T17227 Vernakalant Hydrochloride 748810-28-8 99.04%
Vernakalant Hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.
T15260 Evenamide 1092977-61-1 99.15%
Evenamide is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
TP1852L Myomodulin acetate(110570-93-9 free base) TP1852L 99.24%
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.
T5850 Benzamil 2898-76-2 99.3%
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane ...
T0440 Oxcarbazepine 28721-07-5 99.31%
Oxcarbazepine is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activit...
T6782L Benzocaine xHCl(94-09-7(free base)) T6782L 99.37%
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
T8711 PF-05186462 1235406-03-7 99.37%
PF-05186462 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
T2342 Raxatrigine 934240-30-9 99.39%
Raxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
T0862 Diphenidol hydrochloride 3254-89-5 99.42%
Diphenidol hydrochloride, a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.
EIPA
TQ0157
EIPA (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
Sodium ionophore III
T3956
Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.
Primidone
T0024
Primidone is an anticonvulsant of the pyrimidinedione class.
Meticrane
T0275
Meticrane is a sulphonamide-derivative with thiazide-like diuretic activity.
Mepivacaine hydrochloride
T0946
Mepivacaine Hydrochloride is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties.
Hydroquinidine
T1334
Dihydroquinidine is an organic compound, used as an antiarrhythmic agent.
Monensin sodium salt
T1033
Monensin sodium is an antiprotozoal agent produced by Streptomyces cinnamonensis.Monensin sodium salt causes a marked enlargement of the MVBs and regulates exoso...
Eleclazine hydrochloride
T15207
Eleclazine hydrochloride is a novel inhibitor of late Na+ current (IC50: 0.7 uM).
20(S)-Ginsenoside Rg3
T3402
Ginsenoside Rg3 possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the prol...
Valproic Acid
T7064
Valproic Acid is a branched chain fatty acid which potentially enhances central GABAergic neurotransmission and inhibits Na+ channels. Currently, the various mol...
Procaine hydrochloride
T0802
Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds ...
Vernakalant Hydrochloride
T17227
Vernakalant Hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker.
Evenamide
T15260
Evenamide is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.
Myomodulin acetate(110570-93-9 free base)
TP1852L
Myomodulin acetate is present in two identified aplysia neurons that contain myomodulin A the ARC motor neuron B16 and the abdominal neuron L10.
Benzamil
T5850
Benzamil is an epithelial sodium channel (ENaC) blocker that inhibits sodium transport from (IC50 = 4 nM) and binds to (Kd = 5 nM) bovine kidney cortex membrane ...
Oxcarbazepine
T0440
Oxcarbazepine is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activit...
Benzocaine xHCl(94-09-7(free base))
T6782L
Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).
PF-05186462
T8711
PF-05186462 is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.
Raxatrigine
T2342
Raxatrigine has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.
Diphenidol hydrochloride
T0862
Diphenidol hydrochloride, a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.
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