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Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane.

Cat. No.	Product name	CAS No.	Purity
T80495	MHuwentoxin-IV		98%
T80495	mHuwentoxin-IV, a naturally modified form of Huwentoxin-IV, selectively inhibits tetrodotoxin-sensitive (TTX-S) voltage-gated sodium channels in dorsal root gang...
T80499	Jingzhaotoxin XI		98%
T80499	Jingzhaotoxin XI (JZTX-XI) is a potent inhibitor of sodium conductance, exhibiting an IC50 value of 124 nM, and notably retards the rapid inactivation of Na_v1.5...
T80518	Mambalgin-3		98%
T80518	Mambalgin-3, an acid-sensitive ion channel 1 (ASIC1) inhibitor, has potential applications in analgesia research [1].
T80519	M3-Huwentoxin IV		98%
T80519	m3-Huwentoxin IV (m3-HwTx-IV) is a potent inhibitor of sodium channels (NaV), exhibiting half-maximal inhibitory concentrations (IC50s) of 3.3 nM for hNaV1.7, 6....
T80533	Pterinotoxin-2		98%
T80533	Pterinotoxin-2 is a peptide toxin that acts as a sodium channel inhibitor [1].
T80534	Pterinotoxin-1		98%
T80534	Pterinotoxin-1 is a peptide toxin that functions as an inhibitor of sodium channels [1].
T81134	Sodium Channel inhibitor 4	587843-16-1	98%
T81134	Sodium Channel Inhibitor 4 is a compound that functions as a sodium channel inhibitor [1].
T82936	ATX-II TFA		98%
T82936	ATX-II TFA, a specific Na+ channel modulator toxin, is derived from the venom of the sea anemone (Anemonia sulcata). This compound impedes the inactivation of Na...
T22829	GX-674	1432913-36-4	98%
T22829	GX-674 is a highly potent and selective voltage-gated sodium channel 1.7 (Nav1.7) antagonist with an IC50 value of 0.1 nM measured at -40 mV for the study of inf...
TP1852	Myomodulin	110570-93-9	98%
TP1852	Myomodulin is a neuropeptide present in molluscs, insects, and gastropods.Myomodulin is present in two identified aplysia neurons that contain myomodulin A the A...
TN4697	Odoroside H	18810-25-8	98%
TN4697	Odoroside H has anticancer activities, the cytotoxic effects are induced by the inhibition of the plasma membrane bound Na(+)/K(+)-ATPase.
TN5141	Thevetin B	27127-79-3	98%
TN5141	Thevetin B is a cardiac glycoside and an inhibitor of Na+-, K+-dependent adenosinetriphosphatase (Na+,K+-ATPase) from Thevetia peruviana.
TCA2511	11Beta-hydroxyprogesterone	600-57-7	98%
TCA2511	The progesterone derivatives 11 alpha- and 11 beta-hydroxyprogesterone are potent inhibitors of 11 beta-hydroxysteroid dehydrogenase (isoforms 1 and 2) in vitro ...
TN4276	Isocudraniaxanthone B	199851-52-0	98%
TN4276	Isocudraniaxanthone B may have antimalarial activity.
T12951	Sodium Channel inhibitor 2	653573-60-5	98%
T12951	Sodium Channel inhibitor 2 is a blocker of sodium channel.
TN5234	Vindorosine	5231-60-7	98%
TN5234	Vindorosine has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular sm...
TN2306	Wilfordine	37239-51-3	98%
TN2306	Wilfordine is an insecticidally active alkaloid, Na+-K+-ATPase may be an acting target of wilfordine against some larvae of insect.
T11239	Ethacizine hydrochloride	57530-40-2	98%
T11239	Ethacizine hydrochloride (NIK-244) has antiarrhythmic activity, and its effects are related to cardiac activity and can be used to study arrhythmias and myocardi...
TN5060	Stauntosaponin A	1417887-91-2	98%
TN5060	Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively.
TN4183	Hardwickiic acid	1782-65-6	98%
TN4183	Hardwickiic acid ((-)-Hardwikiic acid) is a natural compound derived from Pulicaria gnaphalodes and is an anti-injury receptor compound. hardwickiic acid blocks ...