T10733 |
CDDO-EA
|
932730-51-3
|
98%
|
|
CDDO-EA is an activator of the Nrf2/antioxidant response element.
|
T6919 |
Omaveloxolone
|
1474034-05-3
|
98%
|
|
Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
|
T13604 |
CDDO-dhTFEA
|
1191265-33-4
|
98%
|
|
CDDO-dhTFEA is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. It restores...
|
T6S1302 |
Carnosol
|
5957-80-2
|
98%
|
|
Carnosol has anti-oxidative, anti-inflammatory, antiproliferative and apoptosis inducing properties. Carnosol enhances the sensitivity of chemoresistant cancer c...
|
T6165 |
Bardoxolone Methyl
|
218600-53-4
|
98%
|
|
Bardoxolone Methyl, an IKK inhibitor, exhibits effective proapoptotic and anti-inflammatory activities.
|
T3743 |
4-hydroxyphenylacetic acid
|
156-38-7
|
98%
|
|
4-hydroxyphenylacetic acid is a major microbiota-derived metabolite of polyphenols. 4-hydroxyphenylacetic acid is involved in the antioxidative action. 4-hydroxy...
|
T0973 |
Pyridoxine
|
65-23-6
|
98%
|
|
Pyridoxine is the 4-methanol form of vitamin B6 and is converted to pyridoxal 5-phosphate in the body. Although pyridoxine and vitamin B6 are still frequently us...
|
T2915 |
Bardoxolone
|
218600-44-3
|
98%
|
|
CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of inducible nitric oxide synthase and inducible COX-2 in INF-γ-activated mouse macr...
|
TN6750 |
2-tert-Butyl-1,4-benzoquinone
|
3602-55-9
|
98%
|
|
2-tert-Butyl-1,4-benzoquinone (TBQ), an electrophilic metabolite of butylated hydroxyanisole (BHA), causes activation of Nrf2 together with S-arylation of its ne...
|
T16331 |
NK-252
|
1414963-82-8
|
98%
|
|
NK-252 is a potential activator of Nrf2. It has great Nrf2-activating potential.
|
TN4234 |
Hydrangenol
|
480-47-7
|
98%
|
|
Hydrangenol is a natural product and can be isolated from Hydrangea serrata leaves. Hydrangenol is an antiphotoaging compound with oral activity. Hydrangenol can...
|
TN1621 |
Eriodictyol-7-O-glucoside
|
38965-51-4
|
98%
|
|
Eriodictyol-7-O-glucoside is an Nrf2 activator conferring protection against Cisplatin-induced toxicity. Eriodictyol-7-O-glucoside is a flavonoid and a free radi...
|
T0153 |
Oltipraz
|
64224-21-1
|
98%
|
|
Oltipraz is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as g...
|
T12253 |
Nrf2-IN-1
|
1610022-76-8
|
98%
|
|
Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).
|
T8704 |
4-hydroxyphenyl acetate
|
3233-32-7
|
98%
|
|
4-Acetoxyphenol Prevents RPE Oxidative Stress-Induced Necrosis by Functioning as an NRF2 Stabilizer
|
T5S1805 |
5,7-Dihydroxychromone
|
31721-94-5
|
98%
|
|
1. 5, 7-Dihydroxychromone isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5, 7-Dihydroxychromone exerts...
|
T3227 |
Danshensu
|
76822-21-4
|
98%
|
|
Danshensu is an active ingredient of Salvia miltiorrhiza with wide cardiovascular benefit.
|
T60487 |
DDO-7263
|
2254004-96-9
|
98%
|
|
DDO-7263 is a 1,2,4-Oxadiazole derivative that upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of...
|
T2794 |
Astilbin
|
29838-67-3
|
98%
|
|
Astilbin is actions Flavonoid phytochemical found in St. John′s wort and Traditional Chinese Medicine herbal preparations.
|
T3717 |
Hinokitiol
|
499-44-5
|
98%
|
|
β-thujaplicin can inhibit ultraviolet B-induced apoptosis in keratinocytes and strongly suggest that the inhibitory mechanism is due to the antioxidant activity ...
|