Ferroptosis

Ferroptosis is a type of programmed cell death dependent on iron and characterized by the accumulation of lipid peroxides, and is genetically and biochemically distinct from other forms of regulated cell death such as apoptosis.

Cat. No.	Product name	CAS No.	Purity
T79359	Anticancer agent 147	2241283-11-2	98%
T79359	Compound 6j (Anticancer agent 147), a sophoridine derivative and ferroptosis inducer, promotes intracellular accumulation of Fe2+, reactive oxygen species (ROS),...
T79639	Lepadin H	412328-25-7	98%
T79639	Lepadin H, a marine alkaloid and ferroptosis inducer, exhibits significant cytotoxicity by promoting p53 expression, escalating ROS production, and enhancing lip...
T79777	GPX4-IN-7		98%
T79777	GPX4-IN-7 (Compound 31), an indirubin derivative, serves as a ferroptosis inducer in colon cancer treatment. Exhibiting potent antitumor properties, it inhibits ...
T79945	Ferroptosis-IN-1		98%
T79945	Ferroptosis-IN-1, a diterpene derived from A. campylantha, functions as a ferroptosis inhibitor with an EC50 of 10 μM and is utilized in the study of neuroinflam...
T82408	Ferroptosis-IN-3		98%
T82408	Ferroptosis-IN-3 (Compound 25), a ferroptosis inhibitor, demonstrates potent activity by inhibiting RSL3-induced ferroptosis in HT-1080 cells (EC50: 8.6 nM). It ...
T0877	Gallic acid	149-91-7	99.95%
T0877	Gallic acid (Benzoic acid) is found in almost all plants. Plants known for their high gallic acid content include gallnuts,grapes,tea,hops and oak bark.
T2401	Alogliptin Benzoate	850649-62-6	99.95%
T2401	Alogliptin Benzoate (SYR 322)(SYR 322), an effective and specific DPP-4 inhibitor (IC50<10 nM), exhibits greater than 10, 000-fold selectivity over DPP-8/9. Alog...
T0687	Simvastatin	79902-63-9	99.95%
T0687	Simvastatin (MK 733) is an HMG-CoA reductase inhibitor (Ki=0.2 nM) with oral activity. Simvastatin has hypolipidemic activity, inhibits hepatic production of cho...
T0191	Linagliptin	668270-12-0	99.95%
T0191	Linagliptin (BI 1356) is a potent, orally bioavailable dihydropurinedione-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity.
T6468	D-glutamine	5959-95-5	99.92%
T6468	D-glutamine, an D type stereoisomer of glutamine, is one of the 20 amino acids which is encoded by the standard genetic code.
T5371	L-BUTHIONINE-(S,R)-SULFOXIMINE	83730-53-4	99.92%
T5371	L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase (Ki <100 μM) that induces oxidative stress in cell...
T0433	Artesunate	88495-63-0	99.91%
T0433	Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria. It is a semi-synthetic derivative of artemisinin that is water-soluble and m...
T4309	CIL56	300802-28-2	99.91%
T4309	CIL56 (CA3) is a small molecule that induces cellular ferroptosis through the production of iron-dependent reactive oxygen species (ROS). It also induces accumul...
T3116	Atorvastatin hemicalcium salt	134523-03-8	99.89%
T3116	Atorvastatin hemicalcium salt (Atorvastatin Calcium), an effective HMG-CoA reductase inhibitor (IC50 = 8 nM), is utilized as a cholesterol-lowering medication.
T6947	Piperlongumine	20069-09-4	99.89%
T6947	Piperlongumine (Piplartine) is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (RO...
T0078	Lapatinib	231277-92-2	99.89%
T0078	Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced ...
T1648	α-Vitamin E	59-02-9	99.89%
T1648	α-Vitamin E (Dexrabeprazole Sodium) is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.
T1457	Deferasirox	201530-41-8	99.89%
T1457	Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.
T2796	Coenzyme Q10	303-98-0	99.88%
T2796	Coenzyme Q10 (CoQ10) (ubiquinone) is a naturally occurring compound, acting as the electron carrier in the mitochondrial respiratory chain.
T8662	UAMC-3203 hydrochloride	2271358-65-5	99.87%
T8662	UAMC-3203 hydrochloride is a potent and selective Ferroptosis inhibitor with an IC50 of 12 nM.