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(1)
By Target- Apoptosis
- Bcl-2 Family(1)
- Carbonic Anhydrase(1)
- Caspase(1)
- Ferroptosis(1)
- ROS(1)
- STAT(1)
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Results for "
target/Ferroptosis/1
" in TargetMol Product Catalog- Inhibitors & Agonists1
STAT3/CAIX-IN-1
T2107903053583-60-8
STAT3/CAIX-IN-1 is a dual-target inhibitor of STAT3 (Kd: 60.03 μM) and CAIX (IC50: 80.45 nM). It induces ferroptosis by elevating reactive oxygen species (ROS) and lipid peroxides. This compound also inhibits cell migration, induces apoptosis, and causes cell cycle arrest in MDA-MB-231 cells. STAT3/CAIX-IN-1 is applicable for research in triple-negative breast cancer (TNBC).
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