Drug Metabolite

Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom oxygenations, reductions, and dehydrogenations, heteroatom dealkylations, hydroxylations, can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No.	Product name	CAS No.	Purity
T6293	Mycophenolate Mofetil	128794-94-5	98%
T6293	Mycophenolate mofetil, an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydroge...
T4710	3-Methoxytyramine hydrochloride	1477-68-5	98%
T4710	3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1). 3-methoxytyramine can be foun...
T8217	Enzalutamide carboxylic acid	1242137-15-0	98%
T8217	Enzalutamide carboxylic acid is an antagonist of androgen receptor (AR) .
T13539	Allopurinol riboside	16220-07-8	98%
T13539	Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside p...
T16338	Norgestimate metabolite Norelgestromin	53016-31-2	98%
T16338	Norelgestromin is one of the active metabolites of norgestimate.It is a steroidal progestin used in contraceptive patches, where it is combined with the estrogen...
T8339	16α-Hydroxyprednisolone	13951-70-7	98%
T8339	16alpha-Hydroxyprednisolone is a stereoselective metabolite of the 22(R) epimer of the glucocorticoid budesonide
T13808	P-Coumaric Acid Ethyl Ester	7362-39-2	98%
T13808	p-Coumaric Acid Ethyl Ester is the ethyl ester of p-Coumaric acid. p-Coumaric Acid is a common dietary polyphenol and also a potent immunosuppressive agent in tr...
T8945L	AST5902 mesylate(2412155-74-7 free base)	T8945L	98%
T8945L	AST5902 mesylate is principal metabolite of Alflutinib in vivo. AST5902 mesylate exerts antineoplastic activity.
T5420	Cycloguanil hydrochloride	152-53-4	98%
T5420	Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodiu...
T10157	Regorafénib N-oxyde (M2)	835621-11-9	98%
T10157	Regorafénib N-oxyde M2 is an active metabolite of Regorafenib. Regorafenib is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, RET, Kit, and Raf-1 (IC50s: 13/4.2...
T10147	4-Hydroxymephenytoin	61837-65-8	98%
T10147	4-Hydroxymephenytoin is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.
T8547	DCBA	72236-23-8	98%
T8547	DCBA is a endogenous metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). The concentration of DCBA in urine can assess exposure to DEET.
T16339	Norverapamil hydrochloride	67812-42-4	98%
T16339	Norverapamil hydrochloride ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glyc...
T7174	Urolithin A	1143-70-0	98%
T7174	Urolithin A is a secondary metabolite of ellagic acid, a polyphenolic antioxidant, that has antiproliferative, anti-inflammatory, and anti-oxidant properties.
T4281	Endoxifen	110025-28-0	98%
T4281	(E/Z)-Endoxifen is an active metabolite of tamoxifen produced by the sequential action of cytochrome P450 (CYP) isoforms, including CYP2D6. It is a strong anti-e...
T36061	N-Desmethyl Sildenafil	139755-82-1	98%
T36061	N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor.
Fr13756	Isonicotinic acid	55-22-1	98%
Fr13756	Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinoly...
T13621	CNDAC hydrochloride	134665-72-8	98%
T13621	CNDAC hydrochloride, a nucleoside analog, is a metabolite of the sapacitabine.
T16045	Methotrexate metabolite	19741-14-1	98%
T16045	Methotrexate metabolite (DAMPA) is the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist. Methotrexate is used as a chemotherapeutic age...
T1327	Nortriptyline hydrochloride	894-71-3	98%
T1327	Nortriptyline hydrochloride is a metabolite of AMITRIPTYLINE that is also used as an antidepressive agent. Nortriptyline is used in major depression, dysthymia, ...