zearalenone

Zearalenone (F2 toxin) is a mycotoxin produced mainly by fungi belonging to the genus Fusarium in foods and feeds. Possess oestrogenic activity in cattle, pigs and sheep, with low acute toxicity. Causes precocious development of mammae and other estrogenic effects in young gilts.

Zearalenone-13C18 is intended for use as an internal standard for the quantification of zearalenone by GC- or LC-MS. Zearalenone (T5625) is a mycotoxin that has been found inFusariumand has estrogenic activities.1It binds to human estrogen receptor α (ERα) and ERβ (IC50s = 9 and 5.8 nM, respectively).2Zearalenone induces precocious development of mammary tissues in young female pigs and prepucial enlargement in young male pigs.3Zearalenone (1.5-5 mg/kg of diet) induces hyperestrogenism in pigs. It also induces degeneration of meiotic chromatin in oocytes and reduces fertility in pigs when administered at a dose of 200 μg/kg.4Zearalenone has been found as a contaminant in wheat, maize, and barley and livestock feeds.3,4

(8S)-Methyl zearalenone (ZEA analogue 5) is a selective inhibitor of carbonyl reductase 1 (CBR1) with an IC50 value of 0.21 μM.

rac Zearalenone-D6 is a deuterated compound of Zearalenone (T5625).

Multifungin (Bromochlorosalicylanilide) is an antifungal agent used in studies of oral candidiasis, reducing fungal populations in stored corn and preventing zearalenone formation and accumulation.

Zearalenone is a nonsteroidal estrogenic mycotoxin produced by Fusarium species that colonizes various grains.

α-Zearalenol is one of the major metabolites of Zearalenone. α-Zearalenol has structural analogy to estrogen, thus α-Zearalenol can bind to estrogen receptors (ERs).

Beta-Zearalenol, a derivative of zearalenone (ZEA) capable of conjugating with glucuronic acid[2], is a mycotoxin produced by Fusarium spp. It induces apoptosis and oxidative stress in mammalian reproductive cells[1].

α-Zearalenol-D5 is a deuterated compound of α-Zearalenol. α-Zearalenol (T13542) has a CAS number of 36455-72-8. α-Zearalenol (T13542) is one of the major metabolites of Zearalenone. α-Zearalenol (T13542) has structural analogy to estrogen, thus α-Zearalenol (T13542) can bind to estrogen receptors (ERs).

Beta-Zearalanol-d5 is a deuterium-labeled version of Beta-Zearalanol. Beta-Zearalanol is a mycotoxin produced by fungi of the genus Fusarium, which can cause apoptosis in mammalian reproductive cells and oxidative stress. It is a derivative of Zearalenone and can conjugate with glucuronic acid.

Zeranol-d5-1 (α-Zearalanol-d5-1) is the deuterium-labeled version of Zeranol. Zeranol is a metabolite of the mycoestrogen zearalenone and acts as an estrogen receptor agonist. Due to its potent estrogenic activity, Zeranol is utilized as a growth promoter in livestock.

α-Zearalenol (Standard) is the standard substance of α-Zearalenol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. α-Zearalenol is one of the major metabolites of Zearalenone. α-Zearalenol has structural analogy to estrogen, thus α-Zearalenol can bind to estrogen receptors (ERs).

Aurofusarin is a secondary metabolite produced by Fusarium graminearum, a prominent fungal pathogen in temperate climate regions that affects major crops. In addition to aurofusarin, Fusarium graminearum synthesizes several other compounds, including monomethylsorbitol, zearalenone C, antibiotic Y, 2-amino-14,16-dimethyloctadecan-3-ol (2-AOD-3-ol), gibberellin, and enniatin.

Zeo is a hapten of zearalenone, featuring an extended linker and alternative binding sites, specifically designed for the creation of immunogens and detection conjugates.

ZEp is an immunogenic hapten derived from zearalenone (ZEN), utilized in immunoassays after the activation of its carboxyl group into the corresponding N-hydroxysuccinimide ester.