triglycerides production

Acipimox (K-9321) is a niacin derivative and nicotinic acid analog with activity as a hypolipidemic agent. Acipimox has special application for the treatment of hyperlipidemia in non-insulin-dependent diabetic patients.

(E/Z)-Squalene ((E/Z)-AddaVax) regulates intracellular reactive oxidant species (ROS) production, induces apoptosis and necrosis in a concentration- and time-dependent manner, accumulates in the liver, and lowers hepatic cholesterol and triglycerides.

Didocosahexaenoin, an omega-3 derivative and diglyceride of DHA synthesized from DHA triglycerides, significantly decreases mitochondrial membrane potential and stimulates ROS (reactive oxygen species) production. It induces apoptosis and exhibits stronger cytotoxic effects on human prostate carcinoma cells compared to DHA [1].

Morolic acid and moronic acid have shown sustained antidiabetic and antihyperglycemic action possibly mediated by an insulin sensitization with consequent changes of glucose, cholesterol and triglycerides, in part mediated by inhibition of 11β-HSD 1. Moro