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Ruthenium Red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (ICa) blocker, blocks Ca2+ uptake and release, and voltage-sensitive Ca2+ channels

Coelenterazine H is a synthetic derivative of coelenterazine (a light-emitting biomolecule).Coelenterazine h (CLZN-h) is more sensitive to Ca 2+ than is the native complex, thus providing a valuable tool for measuring small changes in Ca 2+ concentrations.

Msr-Ratio (Msr-green) (Msr-green) is a ratiometric fluorescent probe specifically designed for the detection of methionine sulfoxide reductase (MSR) activity. It has an excitation wavelength of 375 nm and an emission wavelength of 550 nm. This probe offers the ability to monitor the enzyme activity both in vitro and in live cells, making it a valuable tool for studying MSR function.

DQ-BSA-RED is a red-fluorescently labeled bovine serum albumin derivative specifically designed to monitor lysosomal proteolytic activity. DQ-BSA-RED exhibits excitation and emission maxima at 590 nm and 620 nm, respectively, and contains multiple dye moieties resulting in fluorescence self-quenching until proteolytic cleavage occurs within lysosomes, upon which bright fluorescence is emitted. DQ-BSA-RED therefore enables the visualization and quantification of lysosomal functionality in live-cell assays, while inactive lysosomes fail to generate fluorescence, providing a valuable tool for studying autophagy and intracellular degradation processes.

CIK4, an optimized cage-like electrophilic probe, significantly enhances the coverage of intracellular cysteine residues. It serves as a valuable tool for studying changes in cysteine reactivity and PTMs (post-translational modifications).

Wheat germ agglutinin-AF350 (WGA-AF350) is a plant lectin conjugated with the fluorescent dye AF350, utilized for identifying carbohydrate chains. It serves as a tool for assessing abnormal glycosylation levels in vivo. The specific glycosylation detection sites of Wheat germ agglutinin are bis-GlcNAc and SA.

BP Fluor 594 NHS ester is a widely used tool for modifying proteins or antibodies through the labeling of primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling process is optimal at pH 7-9, forming stable covalent amide bonds. BP Fluor 594 dye supports high molar ratio protein labeling with negligible self-quenching, resulting in brighter conjugates and more sensitive detection. BP Fluor 594 is a bright, water-soluble, pH-insensitive red fluorescent dye effective across a pH range of 4 to 10, with absorption and emission peaks at 590 and 617 nm, respectively. It is compatible with 561 nm and 594 nm laser lines. BP Fluor 594 can bind to various antibodies, peptides, proteins, tracers, and amplification substrates, and it is commonly used to generate stable signals in imaging and flow cytometry.

BP Fluor 488 Azide is a versatile dye. This dye serves as a crucial tool in biological experiments, aiding researchers in observing and analyzing cellular structures, tracking biomolecules, assessing cellular functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications span from basic scientific research to clinical diagnostics. Additionally, dyes like BP Fluor 488 Azide are widely used in traditional areas such as textile dyeing and emerging fields including functional textile processing, food coloring, and dye-sensitized solar cells.

(γ-AmNS)UTP (trisodium) is a fluorescent derivative of UTP utilized for monitoring RNA polymerase activity. Upon RNA incorporation, UMP releases γ-AmNS-PPi, which exhibits higher intrinsic fluorescence than (γ-AmNS)UTP. Additionally, (γ-AmNS)UTP (trisodium) serves as a tool in the research of antimicrobial and antitubercular agents.

HCy-AAN-Bio is a tumor-targeting hemicyanine (HCy) probe designed for in vivo fluorescence/photoacoustic (FL/PA) imaging of legumain. It is specifically cleaved by legumain, generating FL/PA signals. HCy-AAN-Bio shows promise as a powerful tool for the early diagnosis of related cancers.

Biotin TSA (200×) (Biotin Tyramide) is a biotin derivative utilized for tyramide signal amplification in immunohistochemistry and in situ hybridization experiments. It serves as an important tool in research focused on enhancing tyramide signal amplification.

6 TMR Tre is a versatile dye that serves as an essential tool in biological experiments. It aids researchers in visualizing and analyzing cell structures, tracking biomolecules, assessing cellular functions, differentiating cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications range from basic scientific research to clinical diagnostics. Additionally, dyes like this one are widely used in traditional fields such as textile dyeing, as well as in emerging areas like the treatment of functional textiles, food coloring, and dye-sensitized solar cells.

Phalloidin-f-HM-SiR is a versatile dye. It serves as an essential tool in biological experiments, aiding researchers in observing and analyzing cellular structures, tracking biomolecules, assessing cellular functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications span a wide range of fields from basic scientific research to clinical diagnostics. Moreover, dyes are used extensively in traditional domains such as textile dyeing, as well as in emerging areas like functional textile processing, food colorants, and dye-sensitized solar cells.

AF488 NHS ester diTEA is a versatile dye widely used in biological research as a crucial tool. It enables researchers to observe and analyze cellular structures, track biomolecules, assess cell functions, differentiate cell types, detect biomolecules, study tissue pathology, and monitor microorganisms. Its applications span from basic scientific research to clinical diagnostics. Additionally, dyes have extensive uses in traditional fields such as textile dyeing and emerging areas like functional textile processing, food coloring, and dye-sensitized solar cells. AF488 has an emission wavelength (λem) of 520 nm and an excitation wavelength (λex) of 470 nm.

6-HoeHESIR is a versatile dye utilized as an essential tool in biological experiments. It aids researchers in observing and analyzing cell structures, tracking biomolecules, evaluating cell functions, distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications span a wide range from basic scientific research to clinical diagnostics. Additionally, dyes have extensive uses in traditional areas such as textile coloring, as well as emerging fields like functional textile processing, food coloring, and dye-sensitized solar cells.

Photoacoustic contrast agent-2 (acetate) is a versatile dye that serves as an essential tool in biological experiments. It aids researchers in observing and analyzing cell structures, tracking biomolecules, assessing cellular functions, differentiating cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its applications range from fundamental scientific research to clinical diagnostics, as well as traditional fields like textile dyeing and emerging areas such as functional textile treatment, food coloring, and dye-sensitized solar cells.

SERTlight is a fluorescent agent that specifically labels serotonergic neuron cell bodies, dendrites, and axon projections as the fluorescent substrate for the serotonin transporter (SERT). SERTlight is orthogonal in terms of optics, pharmacology, and operations with various genetically encoded sensors, allowing for multiplex imaging. It facilitates the marking of distal 5HT axon projections using GRAB5HT sensors and simultaneously enables imaging of the release of endogenous 5HT, offering a new multifunctional molecular tool for studying the serotonergic system.

Hoechst 33258 trihydrochloride (Bisbenzimide) is a benzimidazole anti-filarial agent. it is fluorescent when it binds to certain nucleotides in DNA, thus providing a tool for the study of DNA replication. it also interferes with mitosis.

Coumberone is a metabolic fluorogenic probe and isoform-selective substrate for all AKR1C isoforms. It can be reduced by all four members of the AKR1C family to its fluorescent alcohol coumberol. Coumberone is a valuable tool for researching AKR1C.

TFMU-ADPr serves as a versatile substrate for assessing poly(ADP-ribose) glycohydrolase (PARG) activity, enabling direct measurement of total PAR hydrolase activity through the liberation of a fluorophore. Exhibiting exceptional reactivity, generality, stability, and usability, TFMU-ADPr is an effective tool for evaluating small-molecule inhibitors and investigating the regulation of ADP-ribosyl catabolic enzymes in vitro [1].

DMTr-4'-Methyluridine-CED-TBDMS phosphoramidite, a dye reagent for oligonucleotide labeling, serves as a pivotal tool in RNA therapeutic research, RNA aptamer development, and ribozyme studies aimed at RNA structure elucidation. This compound offers broad utility as a probe for uncovering RNA structure complexities. For optimal preservation, it should be stored away from light.

Biotin-NH-PSMA-617 is a biotinylated derivative of the small molecule PSMA-617, designed to target prostate-specific membrane antigen (PSMA), which is prominently expressed on prostate tumor cells. The biotinylation of PSMA-617 enhances its ability to bind PSMA, making it a valuable tool in the targeting of prostate cancer cells for diagnostic and therapeutic applications.

3-MeOARh-NTR is an activatable imaging probe characterized by high selectivity and stability, offering a high signal-to-noise ratio specifically for nitroreductase (NTR) detection. It serves as an efficient molecular tool for identifying endogenous NTR [1].

GK16S, a UCHL1 chemogenomic probe, serves as a complementary tool to GK13S for the investigation of UCHL1 function in cellular studies [1].