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tmbim6

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
TMBIM6 antagonist-1
BIA, BAX-inhibitor-1
T8649123134-61-2
TMBIM6 antagonist-1 (BAX-inhibitor-1) is a bax inhibitor
  • $85
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CDC25B-IN-2
T9156134271-74-2
BIA is an inhibitor of the interaction between TMBIM6 and mTORC2, which ultimately blocks AKT activation and cancer progression.
  • $35
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NSCLC-IN-1
T209735
NSCLC-IN-1 (Compound A10-2) targets transmembrane BAX inhibitor motif containing 6 (TMBIM6) to induce mitophagy and ferroptosis. It causes mitochondrial Ca2+ imbalance, resulting in mitochondrial damage. Additionally, NSCLC-IN-1 reduces intracellular glutathione (GSH) levels while increasing the accumulation of lipid peroxides (LPO) and malondialdehyde (MDA). NSCLC-IN-1 is a potent anti-NSCLC compound.
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