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Results for "
t-loop
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Recombinant Protein2
- Antibody Products1
FKB04
T200635
FKB04 is a telomeric repeat binding factor 2 (TRF2) inhibitor that exerts its antitumor activity by disrupting the telomere maintenance mechanisms in hepatocellular carcinoma cells. This leads to T-loop defects, inducing telomere shortening and cellular senescence. Additionally, FKB04 inhibits tumor growth in a human liver cancer xenograft mouse model (by implanting Huh-7 cells in BALB c mice). This compound is utilized in research focused on liver cancer.
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