sst2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
TP2207	Pasireotide Acetate		Somatostatin
	Pasireotide Acetate is a stable cyclohexapeptide somatostatin mimic		Somatostatin
T28743	Seglitide acetate	MK 678,MK678,MK-678	Somatostatin
	Seglitide acetate (MK-678) is a selective agonist of sst2 somatostatin receptor.		Somatostatin
TP1346	CYN 154806 TFA	CYN 154806 TFA	Somatostatin
	CYN 154806 TFA is a cyclic octapeptide and an effective selective somatostatin sst2 receptor antagonist. For the recombinant sst2, sst1, sst3, sst4 and sst5 receptors, the pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48...		Somatostatin
T9692	Paltusotine		Somatostatin
	Paltusotine is a nonpeptide, small molecule somatostatin type 2 (SST2) receptor agonist with high oral bioavailability. Paltusotine maintains GH and IGF-1 levels in acromegaly patients		Somatostatin
T39262L	BIM-23190 aceate		Somatostatin
	BIM-23190 aceate, a somatostatin analog, a selective agonist of SSTR2 and SSTR5. BIM-23190 can be used in cancer and acromegaly studies.		Somatostatin
T24860	TC-G1003	TC G1003
	TC-G1003 is an effective agonist of the somatostatin sst2 receptor.
TP1877	CYN 154806
	CYN 154806 is a potent and selective somatostatin sst2 receptor antagonist, The pIC50 values are 8.58, 5.41, 6.07, 5.76 and 6.48 for human recombinant sst2, sst1, sst3, sst4 and sst5 receptors respectively.
T22487	(1R,1'S,3'R/1R,1'R,3'S)-L-054,264		Others
	somatostatin sst2 receptor agonist		Others
TP2122	Seglitide
	Peptide agonist for sst2 and sst5 somatostatin receptors. IC50/Kd values (nM) at cloned human somatostatin receptors are: > 1000 (sst1), 0.2 - 1.5 (sst2), 27 - 36 (sst3), > 127 (sst4), and 0.06 - 23 (sst5).
T32511L	L-796,778 acetate	L-796,778 acetate(217480-25-6 Free base)	Somatostatin
	L-796,778 acetate is a slective somatostatin receptor agonist with IC50 of 24nM for sst3, for sst1, sst2, sst4 and sst5, IC50 is >1000nM.		Somatostatin
T80759	XY-52
	XY-52 (Compound 32), an ST2 (Stimulation-2) inhibitor, exhibits IC50 values of 5.68 μM and 4.59 μM in the AlphaLISA and HEK-Blue assays, respectively. It promotes proinflammatory T-cell proliferation and diminishes plasm...
TP2045	CH 275
	Potent somatostatin receptor 1 (sst1) agonist; displays selectivity for sst1 (IC50 values are 30.9 nM, 345 nM, > 1 μM, > 10 μM and > 10μM for human sst1, sst3, sst4, sst2 and sst5 respectively). Attenuates somatostatin r...
T82883	BIM-23027
	BIM-23027 is a selective sst 2 receptor agonist (EC 50 = 0.32 nM) with effects analogous to the cyclic tetradecapeptide somatostatin (SRIF). It promotes dopamine release through a Glu-dependent mechanism [1] [2].
T76596	PRL 3195
	PRL 3195 is a somatostatin receptor antagonist, exhibiting K i values of 6, 17, 66, 1000, and 1000 nM for human somatostatin receptors sst 5 , sst 2 , sst 3 , sst 1 , and sst 4, respectively [1].
T11800	L-803087		Somatostatin
	L-803087 is a potent and selective agonist of the growth inhibitor sst4 receptor with a Ki value of 0.7 nM for sst4, which is more than 280-fold more selective than other growth inhibitory receptors.L-803087 induced AMPA...		Somatostatin
T76042	Angiopeptin TFA
	Angiopeptin TFA, a cyclic octapeptide analogue of somatostatin, acts as a partial agonist at sst 2/sst 5 receptors, exhibiting IC50 values of 0.26 nM and 6.92 nM, respectively. This compound effectively inhibits the rele...
T25087	Angiopeptin	D-Nal-cys-tyr-trp-lys-val-cys-thr-NH2,Bim 23014 C
	Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.
T13811	Pasireotide ditrifluoroacetate	SOM230 ditrifluoroacetate,Pasireotide ditrifluoroacetate (396091-73-9 free base),Pasireotide TFA salt	Others
	Pasireotide is a stable cyclohexapeptide somatostatin mimic.		Others
T12369	Pasireotide pamoate	SOM230 pamoate	Others
	Pasireotide pamoate is a stable cyclohexapeptide somatostatin mimic. Pasireotide pamoate exhibits antisecretory, antiproliferative, and proapoptotic activity.		Others
T39207	L-803087 TFA
	L-803087 TFA is a highly potent and selective agonist of the somatostatin sst4 receptor, exhibiting a Ki value of 0.7 nM. It displays a remarkable selectivity, being over 280-fold more preferential for the sst4 receptor ...