sodium citrate

Sodium citrate (Natrocitral) is the sodium salt of citric acid.Citric acid trisodium induces apoptosis and cell cycle arrest at G2 M phase and S phase. Sodium citrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities.

Sodium citrate dihydrate (Trisodium citrate dihydrate) is an anticoagulant, and also used as a buffer and food preservatives.

Sodium citrate monobasic (Citric acid monosodium salt) is a biochemical reagent.

Sodium Citrate Buffer, 0.5M, pH 6.5, is a commonly used buffer solution composed mainly of citric acid and disodium hydrogen phosphate. It is employed in heat-induced epitope retrieval (HIER) to restore antigenicity in formalin-fixed, paraffin-embedded tissues where some epitope antigenicity has been lost. This buffer is the preferred solution for most antibodies.

Sodium Citrate Buffer, 0.5M, pH 5.0 is a commonly utilized buffer solution, comprising primarily of citric acid and disodium hydrogen phosphate. It is employed in heat-induced epitope retrieval (HIER) to restore the loss of antigenicity in epitopes within formalin-fixed paraffin-embedded tissues. This solution is the preferred choice for most antibodies and can dissolve captisol in animal tumor models.

Sodium Citrate Buffer, 0.1M, pH 4.0, is a widely used buffer solution composed mainly of citric acid and disodium hydrogen phosphate. It is utilized for heat-induced epitope retrieval (HIER) to restore the antigenicity of certain epitopes that may be lost in formalin-fixed, paraffin-embedded tissue. This buffer is the preferred solution for most antibodies and can also be employed for the hydration of liposome membranes.

Sodium citrate dihydrate, used in molecular biology, serves as an antacid for research on neutralizing stomach acid. Sodium citrate dehydrate is commonly employed in the preparation of biological buffers for molecular biology studies.

Sodium Citrate Buffer, 0.5M, pH 5.5 is a commonly used buffer solution primarily composed of citric acid and disodium hydrogen phosphate (Na2HPO4). It is utilized in heat-induced epitope retrieval (HIER) to reverse the loss of antigenicity in epitopes within formalin-fixed, paraffin-embedded tissues. This buffer is the preferred solution for most antibodies.

Sodium Citrate Buffer, 0.5M, pH 6.0, is a commonly used buffer comprising citric acid and disodium hydrogen phosphate. It is utilized for RNA separation and antigen detection in tissue samples.

BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).

SLC13A5-IN-1 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5) that completely blocks the uptake of 14C-citrate, with an IC50 of 0.022 μM in HepG2 cells.

PF-06761281 (Compound 4a) is a potent and partially selective sodium-coupled citrate transporter protein (NaCT SLC13A5) inhibitor with IC50 values of 0.51, 13.2, and 14.1 µM for NaCT, NaDC, and NaDC, respectively, and has the advantage of being orally active, reducing hepatic and renal uptake of citrate and plasma glucose concentration for metabolic diseases.

PF-06649298 is an inhibitor of sodium-coupled citrate transporter which specifically interacts with NaCT with an IC 50 value of 16.2 μM to inhibits the transport of citrate in human hepatocytes. PF-06649298 can be used in regulating metabolism of glucose and metabolism of lipid [1] [2].

LBA-3, a selective and orally active inhibitor of the sodium-coupled citrate transporter SLC13A5, exhibits an IC50 of 67 nM. This compound effectively reduces triglyceride and total cholesterol levels in both oleic and palmitic acid (OPA)-stimulated AML12 cells and PCN-stimulated primary mouse hepatocytes, as well as in mouse models, without showing detectable toxicity. Additionally, LBA-3 is permeable to the blood-brain barrier [1].

Methyl 2-acetamido-2-deoxy-4,6-O-benzlydene-O-β-D-glucopryanoside is a reagent used in biochemical reactions.

Blood Enrichment Medium is utilized for the enrichment culture of pathogens present in the blood. Its composition includes peptone, beef extract, sodium chloride, glucose, sodium citrate, p-aminobenzoic acid, magnesium sulfate, and phenol red.