sodium citrate

Sodium citrate (Natrocitral) is the sodium salt of citric acid.Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase. Sodium citrate cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities.

Sodium citrate dihydrate (Trisodium citrate dihydrate) is an anticoagulant, and also used as a buffer and food preservatives.

Sodium citrate monobasic (Citric acid monosodium salt) is a biochemical reagent serving as a preservative, emulsifier, chelating agent, and buffer. Monobasic sodium citrate induces apoptosis in HaCaT cells and causes cell cycle arrest at the G2/M and S phases. It also induces hepatic oxidative damage by reducing antioxidant enzyme activity.

Sodium Citrate Buffer (0.5M, pH 6.5) is a sodium citrate buffer with a pH of 6.5. It is a commonly used acidic biochemical buffer suitable for heat-induced epitope retrieval (HIER) to reduce antigen masking caused by protein cross-linking in formalin-fixed, paraffin-embedded (FFPE) tissues. Sodium Citrate Buffer (0.5M, pH 6.5) also maintains stable pH within its effective buffering range, making it suitable for stabilizing certain proteins and enzymes.

Sodium Citrate Buffer, 0.5M, pH 5.0 is a sodium citrate buffer solution with a pH of 5.0. It is a commonly used acidic biochemical buffer suitable for heat-induced epitope retrieval (HIER) to reduce antigen masking caused by protein cross-linking in formalin-fixed, paraffin-embedded (FFPE) tissues. Sodium Citrate Buffer, 0.5M, pH 5.0 also maintains a stable pH within its effective buffering range, making it suitable for stabilising certain proteins and enzymes.

Sodium Citrate Buffer, 0.1M, pH 4.0 is a sodium citrate buffer at pH 4.0, a commonly used acidic biochemical buffer. It improves RT-PCR amplification efficiency in long-term stored or formalin-fixed samples and is also suitable for antigen retrieval. Sodium Citrate Buffer, 0.1M, pH 4.0 also maintains stable pH values within its effective buffering range.

Sodium Citrate Buffer (0.5M, pH 5.5) is a sodium citrate buffer with pH of 5.5. It is a commonly used acidic biochemical buffer suitable for heat-induced epitope retrieval (HIER) to reduce antigen masking caused by protein cross-linking in formalin-fixed, paraffin-embedded (FFPE) tissues. Sodium Citrate Buffer (0.5M, pH 5.5) also maintains stable pH within its effective buffering range, making it suitable for stabilizing certain proteins and enzymes.

Sodium Citrate Buffer (0.5M, pH 6.0) is a sodium citrate buffer with a pH of 6.0. It is a commonly used acidic biochemical buffer suitable for RNA isolation and antigen detection in tissue samples. Sodium Citrate Buffer (0.5M, pH 6.0) also maintains a stable pH within its effective buffering range, making it suitable for stabilizing certain proteins and enzymes.

Tween 40 is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).

SLC13A5-IN-1 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5) that completely blocks the uptake of 14C-citrate, with an IC50 of 0.022 μM in HepG2 cells.

Octanoyl Coenzyme A (sodium salt) is a derivative of fatty acyl coenzyme A. Octanoyl coenzyme A sodium salt inhibits citrate synthase and glutamate dehydrogenase with an IC50 of 0.4–1.6 mM.

PF-06761281 (Compound 4a) is a potent and partially selective sodium-coupled citrate transporter protein (NaCT/SLC13A5) inhibitor with IC50 values of 0.51, 13.2, and 14.1 µM for NaCT, NaDC, and NaDC, respectively, and has the advantage of being orally active, reducing hepatic and renal uptake of citrate and plasma glucose concentration for metabolic diseases.

PF-06649298 is an inhibitor of sodium-coupled citrate transporter which specifically interacts with NaCT with an IC 50 value of 16.2 μM to inhibits the transport of citrate in human hepatocytes. PF-06649298 can be used in regulating metabolism of glucose and metabolism of lipid [1] [2].

LBA-3, a selective and orally active inhibitor of the sodium-coupled citrate transporter SLC13A5, exhibits an IC50 of 67 nM. This compound effectively reduces triglyceride and total cholesterol levels in both oleic and palmitic acid (OPA)-stimulated AML12 cells and PCN-stimulated primary mouse hepatocytes, as well as in mouse models, without showing detectable toxicity. Additionally, LBA-3 is permeable to the blood-brain barrier [1].

Blood Enrichment Medium is utilized for the enrichment culture of pathogens present in the blood. Its composition includes peptone, beef extract, sodium chloride, glucose, sodium citrate, p-aminobenzoic acid, magnesium sulfate, and phenol red.