sildenafil

Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertension.

Pyrazole N-Desmethyl sildenafil (Compound 10) is an analogue of Sildenafil. At a concentration of 100 µM, it inhibits the activity of the Trypanosoma brucei phosphodiesterase TbrPDEB1 by 16%.

O-Desethyl sildenafil is a metabolite of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .1

N-Desmethyl Sildenafil is the major metabolite of Sildenafil, a potent phosphodiesterase type 5 (PDE5) inhibitor.

N-Desmethyl sildenafil is a major metabolite of sildenafil . N-Desmethyl sildenafil is formed via oxidative metabolism of sildenafil by the cytochrome (CYP) P450 isoforms CYP3A4, CYP3A5, and CYP3A7.

Sildenafil chlorosulfonyl is a synthetic intermediate in the synthesis of the phosphodiesterase 5 (PDE5) inhibitor sildenafil .1It is also a potential impurity found in commercial preparations of sildenafil. 1.Nagaraju, V., Sreenath, D., Rao, J.T., et al.Separation and determination of synthetic impurities of sildenafil (Viagra) by reversed-phase high-performance liquid chromatographyAnal. Sci.19(7)1007-1011(2003)

Sildenafil nitrate is a selective inhibitor of PDE5 (type 5 cGMP phosphodiesterase) which catalyzes the hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP).

Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.

Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.

Sildenafil-d8 is a deuterated compound of Sildenafil. Sildenafil has a CAS number of 139755-83-2. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor, used to treat erectile dysfunction and reduce symptoms of pulmonary arterial hypertension (PAH).

N-Desmethyl Sildenafil-d8 is a deuterated compound of N-Desmethyl Sildenafil. N-Desmethyl Sildenafil has a CAS number of 139755-82-1. N-Desmethyl Sildenafil (Desmethylsildenafil) is a prominent metabolite of Sildenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5).

Sildenafil-13C-d3 the 13C and deuterated compound of Sildenafil. Sildenafil has a CAS number of 139755-83-2. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor, used to treat erectile dysfunction and reduce symptoms of pulmonary arterial hypertension (PAH).

Dimethyl Sildenafil-d5 is a deuterated compound of Dimethyl Sildenafil.

Pyrazole N-Desmethyl Sildenafil (Standard) is the standard substance of Pyrazole N-Desmethyl Sildenafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments.

Sildenafil citrate (Standard) is the standard substance of Sildenafil citrate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertension.

N-Desmethyl Sildenafil-d8 hydrochloride is a deuterated compound of N-Desmethyl Sildenafil hydrochloride.

Hydroxythiohomosildenafil (Sulfohydroxyhomo sildenafil) is a sildenafil analog that may be used to study erectile dysfunction.

Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil.

Dimethylsildenafil, a derivative of Sildenafil, is an effective inhibitor of phosphodiesterase type 5 (PDE5) with an IC50 value of 5.22 nM.

Thiosildenafil (Standard) is the standard substance of Thiosildenafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Thiosildenafil is a derivative of the phosphodiesterase 5 (PDE5) inhibitor sildenafil.

Desmethyl thiosildenafil is a type 5 phosphodiesterase (PDE5) inhibitor.

Propoxyphenyl-thiohydroxyhomosildenafil is a bioactive chemical.

Propoxyphenyl-thiohydroxyhomosildenafil (Standard) is the standard substance of Propoxyphenyl-thiohydroxyhomosildenafil, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Propoxyphenyl-thiohydroxyhomosildenafil is a bioactive chemical.

TPN171 is potent PDE5 inhibitor with subnanomolar potency for PDE5 and good selectivity over PDE6, which has the potential for the treatment of pulmonary arterial hypertension (PAH). TPN171 was proven to exert a longer lasting effect than sildenafil in animal models, providing a foundation for a once-daily oral administration for its clinical use.