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(3)
By Target- Apoptosis
- PROTACs(1)
- Others(2)
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Results for "
sf3b1
" in TargetMol Product Catalog- Inhibitors & Agonists6
- PROTAC Products1
- Natural Products1
- Antibody Products3
Pladienolide B
T16551445493-23-2
Pladienolide B is a potent spliceosome inhibitor, a macrolide isolated from Streptomyces obtusususus Mer-12, which targets the SF3B1 subunit of the spliceosome.Pladienolide B exerts its antitumor effects by inhibiting pre-mRNA splicing and inducing necrosis.Pladienolide B possesses antitumor activity and can be used to study leukemia and lymphoid tumors. Pladienolide B has antitumor activity and can be used to study leukemia and lymphoid tumors.
- $347
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