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Search Results for " sedation "

Targets

15

Compounds

2

Natural Products

Cat No. Product Name Synonyms Targets
T2524 Dexmedetomidine Adrenergic Receptor
Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is by means of General Anesthesia.
T1180 Blonanserin AD-5423 Dopamine Receptor , Sigma receptor , 5-HT Receptor , Adrenergic Receptor
Blonanserin (AD-5423) is an atypical antipsychotic approved in Japan in January, 2008. Relative to many other antipsychotics, blonanserin has an improved tolerability profile, lacking side effects such as extrapyramidal ...
T2150 Guanfacine hydrochloride Tenex,Intuniv,Guanfacine Adrenergic Receptor
Guanfacine hydrochloride (Intuniv) is a centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
T6579 Medetomidine hydrochloride MPV785,Medetomidine HCl,Domitor Adrenergic Receptor
Medetomidine hydrochloride (MPV785) is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.
T6466 Dexmedetomidine hydrochloride Precedex,(+)-Medetomidine hydrochloride,(S)-Medetomidine hydrochloride,Dexmedetomidine HCl Adrenergic Receptor
Dexmedetomidine hydrochloride (Precedex) is an imidazole derivative that is an agonist of the adrenergic alpha-2 receptor. It is closely-related to MEDETOMIDINE, which is the racemic form of this compound.
T21390 Fexofenadine Carboxyterfenadine,Telfast,MDL 16.455,Allegra Histamine Receptor
Fexofenadine (Carboxyterfenadine), an antihistamine pharmaceutical drug, is used to treat allergy symptoms, such as nasal congestion, hay fever, and urticaria. Compared to first-generation antihistamines, Fexofenadine is...
T2335 Ebastine Ebastel,LAS-W 090,Ebastin,Kestine,RP64305 Histamine Receptor
Ebastine (Kestine) (trade names Evastin, Kestine, Ebastel, Aleva) is a non-sedating H1 antihistamine. It does not penetrate the blood-brain barrier and thus allows an effective block of the H1 receptor in peripheral tiss...
T1240 Flumazenil Ro 15-1788 GABA Receptor
Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel openi...
T28378 PF-0713 PF 0713,PF713
PF 0713, a GABAA receptor agonist, is used as an intravenous sedative-hypnotic for general anaesthesia, ICU sedation, procedural sedation, chemotherapy.
T29008 Triclofos Sodium SCH-10159,SCH 10159,SCH10159
Triclofos Sodium is used to treat insomnia and used for sedation.
T60297 Triclofos
Triclofos is a potent, orally active sedative. Triclofos is hydrolyzed rapidly into trichloroethanol (TCEOH) and monosodium phosphate in vivo, which helps the sedation [1].
T72240 Romifidine hydrochloride
Romifidine hydrochloride, an α2 adrenergic receptor agonist, induces sedation effects in vivo.
T29227 ZK-91296 ZK 91296,ZK91296
ZK-91296 is a GABA receptor agonist. ZK 91296 can reduce anxiety in animals at doses well below those causing sedation. ZK 91296 may possess pharmacological selectivity for a particular type of BZ receptor interaction, p...
T41183 Helianorphin-19
Helianorphin-19 is a high affinity, potent and selective κ-opioid receptor (KOR) agonist (Ki = 25 nM; EC50= 45 nM). Helianorphin-19 exhibits approximately 200-fold selectivity for KOR over μ and δ-opioid receptors.In viv...
T60943 Tiapride
Tiapride is an atypical neuroleptic agent without propensity for causing catalepsy and sedation. Tiapride is a selective antagonist of dopamine D2-receptor with IC 50 values of 1440, 45.8, >100, and 11.7 μM for D1; D2; D...
Cat No. Product Name Synonyms Targets
T2800 L-Theanine Apoptosis , Others
L-Theanine is a relaxing and nondietary amino acid found pretty much exclusively in teas from Camellia sinensis and is known to promote relaxation without sedation.
TN4519 Mesuaxanthone A Others
Mesuaxanthone A and mesuaxanthone B are two yellow pigments.They produce varying degrees of C.N.S. depression characterised by ptosis, sedation, decreased spontaneous motor activity, loss of muscle tone, potentiation of ...
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