salicylanilide

Salicylanilide (2-Hydroxybenzanilide)s are a group of compounds with antiviral potency, antibacterial and antifungal activities.

Closantel (R-31520), a salicylanilide anthelmintic compound, shows different anthelmintic spectra and obvious toxicity in mammals.

Closantel is a salicylanilide anthelmintic compound; exhibits different anthelmintic spectra and apparent toxicity in mammals.

4'-Chlorosalicylanilide is a useful organic compound for research related to life sciences. The catalog number is T64534 and the CAS number is 3679-63-8.

Osalmid (Oxaphenamide) is a choleretic drug, inhibits ribonucleotide reductase activity by targeting ribonucleotide reductase small subunit M2 (RRM2).

Multifungin (Bromochlorosalicylanilide) is an antifungal agent used in studies of oral candidiasis, reducing fungal populations in stored corn and preventing zearalenone formation and accumulation.

Tribromsalan (3,5,4'-Tribromosalicylanilide) is an inhibitor of Mycobacterium tuberculosis and abscess bacillus, inhibiting IkappaBalpha phosphorylation to suppress NF-kappaB signaling.

SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide. SARS-CoV-2-IN-14 was more stable than niclosamide in the determination of human plasma and liver S9 enzyme. Oral administration of SARS-CoV-2-IN-14 can improve its bioavailability and half-life.

Oxyclozanide (Oxyclozanid) is a salicylanilide anthelmintic used in grazing animals for fasciola and cestode infestations.

Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.

Rafoxanide 13C6 is a labeled Rafoxanide . Rafoxanide is a salicylanilide used as an antiparasitic agent.

Antibacterial agent 116, a benzophenone-containing salicylanilide compound, exhibits potent antibacterial activity by inhibiting peptidoglycan formation. It is employed as a photoaffinity probe to label Acinetobacter baumannii penicillin-binding protein (PBP1b), thereby blocking the propagation pathway and disrupting the growth of the peptidoglycan chain.

Niclosamide-13C6 is the 13C6-labeled form of Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide with anthelmintic and potential antineoplastic properties. It inhibits STAT3 with an IC50 of 0.25 μM in HeLa cells and suppresses DNA replication in cell-free assays.

Closantel-13C6 is the 13C6-labeled version of Closantel. Closantel is a halogenated salicylanilide with potent antiparasitic properties. It serves as an effective and highly specific inhibitor of the chitinase enzyme (OvCHT1) from Onchocerca volvulus, showing an IC50 of 1.6 μM and a Ki of 468 nM. Closantel also inhibits the molting of Haemonchus contortus from the L3 to L4 stage.

Rafoxanide (Standard) is the standard substance of Rafoxanide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.