s. enteritidis

Glycol chitosan, a chitosan derivative with hydrophilic ethylene glycol branches, inhibits E. coli, S. aureus, and S. enteritidis growth (MICs: 4 μg/mL, 32 μg/mL, and <0.5 μg/mL), and enhances membrane permeability and leakage in Glycine max [Harosoy 63W] cells.

Cathelicidin-2 (CATH-2) (128-153) is a synthetic antimicrobial peptide derived from amino acids 128-153 of chicken CATH-2, demonstrating activity against pathogens such as E. coli, S. aureus, S. enteritidis, and B. globigii in a dose-dependent manner. At a concentration of 40 µM, it induces hemolysis in chicken erythrocytes without exhibiting cytotoxicity towards human peripheral blood mononuclear cells (PBMCs). Additionally, it stimulates the production of the chemokine CCL2 and suppresses LPS-induced secretion of TNF-α, IL-6, IL-8, and IL-10 in human PBMCs.

Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast cancer cells.

Lipopolysaccharides, from S. enterica (Salmonella enterica) serotype enteritidis, are endotoxins derived from this serotype known for causing enteritis and serve as TLR-4 activators. This S-type LPS triggers the immune system's pathogen-associated molecular patterns (PAMP) and induces the secretion of exosomes. It consists of a typical tripartite structure: the O antigen, core oligosaccharide, and lipid A. These lipopolysaccharides can provoke a systemic inflammatory response, leading to increased plasma levels of TNF-α, IFN-γ, IL-6, IL-10, and nitrates.