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qr 2

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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    TargetMol | All_Pathways
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Nrf2-ARE/hMAO-B/QR2 modulator 1
T603953035124-25-2
Nrf2-ARE/hMAO-B/QR2 modulator 1, a resveratrol derivative and multi-target-directed ligand (mtdl), activated the NRF2-ARE pathway (CD = 9.83 μM), selectively inhibited hMAO-B and QR2(quinone reductase-2,NQO2) (IC 50 = 8.05 and 0.57 μM), and was able to promote hippocampal neurogenesis and exert neuroprotective and antioxidant effects in an Alzheimer's disease model.
  • $35
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S29434
T7149874484-20-5
S29434 (NMDPEF) is a potent, competitive inhibitor of quinone reductase 2 (QR2), with an IC50 range of 5-16 nM.
  • $51
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Xanthohumol D
TN2314274675-25-1
Xanthohumol and xanthohumol D are potent inducers of quinone reductase, suggests that they could be used as chemoprevention agents.
  • $249
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2-Hydroxy-3-(hydroxymethyl)anthraquinone
TN276268243-30-1
2-Hydroxy-3-(hydroxymethyl)anthraquinone exhibits quinone reductase (QR)- inducing activity in Hepa lclc7 cells, with the concentration required to double QR activity of 0.94 microM.
  • $260
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