plant pathogenic fungus

Fenhexamid (Elevate), a sterol biosynthesis inhibitor, shows antifungal activity against the plant pathogenic fungus. Fenhexamid is used for agriculture and is present in measurable amounts in fruits and vegetables.

Pyrenocine A is a fungal metabolite that has been found inP. terrestrisand has diverse biological activities.1It inhibits the asexual spore germination of the plant pathogenic fungiF. oxysporum,F. solani,M. hiemalis, andR. stolonifer(EC50s = 14, 20, 20, and 25 μg/ml, respectively). Pyrenocine A is active againstB. subtilis,S. aureus, andE. coli(IC50s = 30, 45, and 200 μg/ml, respectively). It inhibits onion seedling elongation (EC50= 4 μg/ml). Pyrenocine A is also a phytotoxin that inhibits lettuce seed germination and rice seedling elongation.2,3 1.Sparace, S.A., Reeleder, R.D., and Khanizadeh, S.Antibiotic activity of the pyrenocinesCan. J. Microbiol.33(4)327-330(1987) 2.Sato, H., Konoma, K., and Sakamura, S.Phytotoxins produced by onion pink root fungus, Pyrenochaeta terrestrisAgric. BioI. Chem.43(11)2409-2411(1979) 3.Sato, H., Konoma, K., Sakamura, S., et al.X-Ray crystal structure of pyrenocine A, a phytotoxin from Pyrenochaeta terrestrisAgric. BioI. Chem.45(3)795-797(1981)

OM173-αA is a quinone bacterial metabolite that inhibits the growth of the bacteria M. gallisepticum, M. pneumoniae, and S. aureus. OM173-αA also inhibits the growth of the plant pathogenic fungus P. oryzae and several species of Trichophyton.

Piliformic acid is a fungal metabolite found in [N. pseudotrichia] with diverse biological activities. It is cytotoxic to BC-1 human breast cancer cells (IC50 = 5 μg ml) and active against [L. braziliensis] amastigotes (IC50 = 78.5 μM). It also shows activity against the plant pathogenic fungi [C. gloeosporioides] (MIC = 292 μM).

Cryptosporiopsin A is a polyketide that has been found in Cryptosporiopsis and has antifungal activity. It is active against the plant pathogenic fungus P. viticola and the plant pathogenic fungi A. cochliodes, P. ultimum, and R. solani (MICs = 20, 40, and 50 µg ml, respectively).

Ascochin, an isocoumarin derivative and fungal metabolite identified in Ascochyta, demonstrates antimicrobial activity. At a concentration of 0.5 mg/disc, it inhibits Bacillus megaterium (the bacterium), Mycosphaerella violaceum (the plant pathogenic fungus), and Chlorella fusca (the alga) in agar diffusion assays.

Uridine diphosphate glucuronic acid ammonium (UDP-α-D-glucuronic acid ammonium) is a precursor of many plant cell wall polysaccharides and is required for the production of seed mucilage.Uridine diphosphate glucuronic acid ammonium is a precursor of pathogenic fungi. ammonium is a key metabolite for pod polysaccharide synthesis in the pathogenic fungus Cryptococcus neoformans.

Flutolanil is a benzanilide fungicide. It is active against a panel of 241 field isolates of the plant pathogenic fungus R. solani when grown in flutolanil-enriched growth media. Flutolanil inhibits R. solani hyphal growth and infection cushion formation on rice plant leaf sheaths. It is toxic to zebrafish embryos, larvae, and adults. Formulations containing flutolanil have been used to control fungal infections on rice crops.

Septeremophilane E, a compound extracted from Septoria rudbeckiae—a plant pathogenic fungus found on the halophyte Karelinia caspia—significantly reduces nitric oxide (NO) production [1].

2-Methoxyanofinic acid is active against the plant pathogenic fungus Cladosporium cucumerinum.

Linearmycin A is a polyene antibiotic found in [Streptomyces]. It exhibits activity against bacteria [S. aureus] and [E. coli] (MICs = 3.1 and 1.6 μg disc, respectively), fungi [S. cerevisiae] and [C. albicans] (MICs = 0.1 and 1.6 μg disc, respectively), and the plant pathogenic fungus [A. niger] (MIC = 0.2 μg disc) in disc assays. Linearmycin A also induces lysis and degradation of [B. subtilis] as a component of [Streptomyces Mg1] extract.

Dendryphiellin D, a compound extracted from the plant pathogenic fungus Septoria rudbeckiae found on the halophyte Karelinia caspia, significantly reduces nitric oxide (NO) [1] production.

Kushenol I is a GABAA receptor modulator, it exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).Kushenol I is shown to be active against the plant pathogenic fungus Cladosporium cucumerinum.

Protoneogracillin, a furostanol glycoside, exhibits anti-fungal activity against the plant pathogenic fungus P. oryzae (MMDC=94.0 μM) and cytotoxic activity against K562 cancer cells (IC 50 =6.6 μM) [1] [2].