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pks13-in-2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Pks13-IN-2
T205621
Pks13-IN-2 (Compound 43) is an orally active inhibitor of Pks13. It exhibits inhibitory activity against Mycobacterium tuberculosis H37Rv, with a MIC of 0.8-1.8 μM. Pks13-IN-2 demonstrates good metabolic stability in mouse liver microsomes and hepatocytes, making it suitable for tuberculosis research.
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Thiophene-2
Thiophene-2,TP2
T40520420089-51-6
Thiophene-2 (TP2) is a targeted inhibitor of polyketide synthase 13 (Pks13), specifically designed to disrupt mycolic acid biosynthesis, effectively inducing rapid cell death in mycobacteria. It demonstrates notable anti-tuberculosis activity and exhibits a minimum inhibitory concentration (MIC) value of 1 μM against Mycobacterium tuberculosis.
  • $970
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