piribedil

Piribedil (Trivastan) is a dopamine D2 agonist, used in the treatment of Parkinson's disease.

dopamine agonist

Piribedil-D8 is the deuterium labeled Piribedil (T3278), which is an agent of antiparkinsonian.

Piribedil hydrochloride can be used in the parkinson's disease, circulatory disorders, cancers research. Piribedil hydrochloride inhibits MLL1 methyltransferase activity with EC50 value of 0.18 μM. Piribedil hydrochloride is a potent and orally active agonist of dopamine D2 and dopamine D3 as well as the antagonist of α2-adrenoceptors [1] [2] [3] [4].

Piribedil N-oxide, a metabolite of the dopamine receptor agonist piribedil, represents a chemical compound involved in the metabolic processing of its parent compound, piribedil.

Piribedil Maleate is a direct agonist of dopamine that acts by showing selectivity for the D3 subtype.

S584 dihydrochloride is an orally active catechol metabolite of Piribedil, possessing anti-lipid peroxidation activity. It significantly inhibits lipid peroxidation in rat synaptosomes under both baseline conditions and Fe³⁺ stimulation. Furthermore, S584 dihydrochloride effectively counteracts the elevation of thiobarbituric acid reactive substances (TBARS) in the brains of mice exposed to hyperoxia and normal air.