picolinamide

Picolinamide (Picolinoylamide) is found to be a strong inhibitor of poly (ADP-ribose) synthetase of nuclei from rat pancreatic islet cells.

N-Methyl-4-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenoxy)picolinamide is a useful organic compound for research related to life sciences and the catalog number is T67100.

N-(2-Hydroxyphenyl)picolinamide is an active molecular compound.

4-(4-Amino-3-fluorophenoxy)-N-methylpicolinamide is an aromatic enigma that is is a metabolite of the antitumor drug rafenil.

4-Bromo-N-methylpicolinamide is a useful organic compound for research related to life sciences. The catalog number is T64454 and the CAS number is 1209459-88-0.

4-(4-Formamidophenoxy)-N-methylpicolinamide is a useful organic compound for research related to life sciences and the catalog number is T64459.

4,6-Dichloro-N-methylpicolinamide is a useful organic compound for research related to life sciences. The catalog number is T64568 and the CAS number is 1379324-09-0.

4-Chloro-N-methylpicolinamide is a useful organic compound for research related to life sciences. The catalog number is T66513 and the CAS number is 220000-87-3.

4-Chloro-N,N-dimethylpicolinamide is a useful organic compound for research related to life sciences. The catalog number is T67664 and the CAS number is 114780-06-2.

Picolinamidoxime is a biochemical substance.

Melanin probe-1, an 18F-picolinamide-based PET probe, is utilized for PET imaging of malignant melanoma. It demonstrates remarkable tumor targeting efficacy, superior tumor imaging contrasts, favorable biodistribution profiles, and robust in vivo stability.

Melanoma is a lethal skin cancer. The early detection of melanoma using positron emission tomography (PET) probes is critical for improving the survival of melanoma patients. Melanin probe-2 is a non-radioactive bromo-picolinamide precursor that has been used for the synthesis of18F-picolinamides based PET probe (melanin probe-1). The tumor-targeting efficacy and imaging property of three melanin probes were evaluated in B16F10 tumor-bearing mice.18F-1 and18F-3 had much lower tumor uptake compared with18F-2 (Melanin probe-2), which were 12.74 ± 1.70, 16.61 ± 2.60, and 16.87 ± 1.23 %ID g at 0.5, 1, and 2 h, respectively[1].