phenytoin sodium

Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .

Fosphenytoin Sodium-d10 is a deuterated compound of Fosphenytoin Sodium. Fosphenytoin Sodium has a CAS number of 92134-98-0. Fosphenytoin is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker

Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. It potentially acts by promoting sodium efflux from neurons in the motor cortex, reducing post-tetanic potentiation at synapses. This prevents cortical seizure foci from spreading to adjacent areas and stabilizes the threshold against hyperexcitability. Additionally, it appears to reduce muscle spindle sensitivity to stretch, causing muscle relaxation.

Phenytoin-d10 is a deuterated isotope-labelled phenytoin for isotope tracing. Phenytoin acts as a voltage-gated Na⁺ channel blocker and t-type Ca²⁺ channel inhibitor, exhibiting antiepileptic activity.

Fosphenytoin disodium (ACC-9653) is a prodrug of phenytoin that is rapidly converted to phenytoin, a voltage-gated sodium channel blocker

Phenytoin (Standard) is the standard substance of Phenytoin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Phenytoin (5,5-Diphenylhydantoin) is a hydantoin derivative and a non-sedative antiepileptic agent with anticonvulsant activity. Phenytoin potentially acts by promoting sodium efflux from neurons located in the motor cortex reducing post-tetanic potentiation at synapses. The reduction of potentiation prevents cortical seizure foci spreading to adjacent areas, stabilizing the threshold against hyperexcitability. In addition, this agent appears to reduce sensitivity of muscle spindles to stretch causing muscle relaxation.