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Cat No. | Product Name | Synonyms | Targets |
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T0453L | DL-Phenylephrine HCl | Eyelo,DL-Phenylephrine hydrochloride | |
DL-Phenylephrine HCl is a selective agonist of the alpha1-adrenergic receptor. | |||
T35576 | Phenylephrine-3-O-Sulfate | ||
Phenylephrine-3-O-sulfate is metabolite of the α1A-adrenergic receptor agonist phenylephrine formed via sulfation. | |||
T68997 | L-Phenylephrine | ||
L-Phenylephrine is an alpha-adrenergic agonist used as a mydriatic, nasal decongestant, and cardiotonic agent. | |||
T22033 | ARC 239 dihydrochloride | Norepinephrine | |
ARC 239 dihydrochloride is a selective α2B adrenoceptor antagonist (pKD values are 8.8, 6.7 and 6.4 at α2B, α2A, and α2D receptors respectively). | |||
T12913 | Siguazodan | SKF 94836 | PDE |
Siguazodan (SKF 94836) is an effective, selective, orally active phosphodiesterase III ((PDE-III)) inhibitor with an IC50 of 117 nM. Siguazodan inhibited phenylephrine induced 5-HT release with an IC50 value of 4.2 μM。 S... | |||
T4563 | Thonzylamine | neohetramine | Histamine Receptor |
Thonzylamine (neohetramine) is an antihistamine and anticholinergic drug. It is available as combination products with Clofedanol or Phenylephrine for temporary relief of symptoms of common cold, hay fever (allergic rhin... | |||
T23557 | Talibegron hydrochloride | ZD2079 hydrochloride,ZD 2079 | Adrenergic Receptor |
Talibegron hydrochloride (ZD2079 hydrochloride) is an β3 adrenergic receptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Relaxes rat mesenteric artery and isolated aorta in vitro. In... | |||
T30427 | Berefrine | ||
Berefrine is an Oxazolidine prodrug of phenylephrine. | |||
T40563 | Sandaracopimaric acid | ||
Sandaracopimaric acid is an anti-inflammatory diterpenoid compound that effectively reduces the contraction of phenylephrine-induced pulmonary arteries. With an EC50 of 43.93 μM, it exhibits noteworthy anti-inflammatory ... | |||
T27164 | DHP-218 | PAK-9,PAK9,PAK 9,DHP218 | |
DHP-218 is a calcium channel antagonist. DHP-218 inhibits Calcium-induced contraction of the rat aorta in high K+ solution with the pA2 value of 9.11. The IC50 value for the inhibitory effects of DHP-218 in high K+-induc... | |||
TP2086 | AdTx1 | ||
Selective, high affinity, non-competitive α1A adrenoceptor antagonist (Ki = 0.35 nM). Exhibits no significant activity against a range of other GPCRs, including α2A, β1 and β2 adrenoceptors. Antagonizes effects of phenyl... | |||
T73083 | Nipradolol | KT 210 ; K 351 ; Hypadil,Hypadil,KT 210,K 351 | |
Nipradolol (KT-210; K-351) is a potent blocker of alpha-1-adrenergic receptors . Nipradolol inhibits the increase of intraocular pressure (IOP) in an albino rabbit model induced by Phenylephrine . Nipradolo suppresses th... | |||
T39281 | AM404 | ||
AM404 is a chemical compound that functions as an inhibitor of endocannabinoid reuptake. It effectively blocks the transport of anandamide, with IC50 values measured in the low micromolar range. Moreover, AM404 exhibits ... | |||
T69127 | Moxisylyte | ||
Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. It is an α1-adrenergic antagonist. Moxisylyte is also used for the short-term treatment of primary Reynaud's syn... | |||
T35989 | CAY10565 | ||
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low m... | |||
T35987 | CAY10563 | CAY10563 | |
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low m... | |||
T35988 | CAY10564 | ||
S-Nitrosothiols (RSNOs) are a class of molecules that function as exogenous and endogenous nitric oxide (NO) donors. RSNOs found in vivo include proteins such as S-nitrosohemoglobin and S-nitrosoalbumin, as well as low m... | |||
T36070 | (±)5(6)-EET | ||
5(6)-EET is a fully racemic version of the enantiomeric forms biosynthesized from arachidonic acid by cytochrome P450 enzymes. In solution, 5(6)-EET degrades into 5,6-DiHET and 5(6)-δ-lactone, which can be converted to 5... |
Cat No. | Product Name | Synonyms | Targets |
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T17310 | Phenylephrine | L-Phenylephrine,(R)-(-)-Phenylephrine | Adrenergic Receptor |
Phenylephrine ((R)-(-)-Phenylephrine) is a selective α1-adrenoceptor agonist ( pKi: 5.86, 4.87 and 4.70 for α1D, α1B, and α1A receptors respectively). | |||
T0453 | Phenylephrine hydrochloride | NCI-c55641,Phenylephrine HCl,(R)-(-)-Phenylephrine hydrochloride | Endogenous Metabolite , Adrenergic Receptor |
Phenylephrine hydrochloride (NCI-c55641) is a selective agonist of the α1-adrenergic receptor. | |||
T7634 | 3-Hydroxymandelic Acid | Endogenous Metabolite | |
3-Hydroxymandelic Acid is a metabolite of Phenylephrine. | |||
T5263 | P-Hydroxymandelic acid | 4-Hydroxymandelic acid | Others , Endogenous Metabolite |
p-Hydroxymandelic acid (4-Hydroxymandelic acid) is an acidic metabolite of p-octopamine and p-synephrine (p-phenylephrine). It is also a naturally occurring metabolite of tyramine. | |||
T2944 | Danshensu sodium salt | Sodium Danshensu,(±)-DanShenSu sodium salt,(±)-DanShenSu sodium sal | P450 , Autophagy |
Danshensu sodium salt (Sodium Danshensu) is sodium salt of danshensu from the widely used Chinese herb Danshen. It can inhibited phenylephrine- and CaCl2-induced vasoconstriction in Ca2+-free medium. | |||
TN1624 | Ethyl cinnamate | Calcium Channel , ROS , NO Synthase | |
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction. Ethyl... | |||
TN1724 | Harmalol hydrochloride | Harmidol hydrochloride | P450 , Antioxidant |
Harmalol hydrochloride (Harmidol hydrochloride) is a β-carboline alkaloid that can be extracted from the seeds of Peganum harmala L. Harmalol hydrochloride is the major metabolite of Harmaline and significantly inhibits ... | |||
TN5061 | Stephanine | Adrenergic Receptor , Antifection | |
l-Stephanine is a potent and highly selective alpha 1 adrenoceptor blocker, inhibits anococcygeus muscle contraction induced by phenylephrine with pA2 values of 6.76. Stephanine shows significant antiplasmodial activitie... |