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Search Result

Search Results for " p50 "

Targets

Tyrosinase

15

Compounds

4

Natural Products

12

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T24584 P505-15 Acetate PRT 062607 Acetate,P505 15 Acetate,PRT-062607 Acetate,PRT062607 Acetate,P50515 Acetate Tyrosinase
P505-15 Acetate is a selective inhibitor of spleen tyrosine kinase that acts by suppressing leukocyte immune function and inflammation and leading to a reduction in arthritis score and attenuated histological damage.
T13336 VTP50469 Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
VTP50469 is a highly selective and orally active inhibitor of Menin-MLL interaction( Ki: 104 pM) and has potently anti-leukemia activity.
TP2164 TP508 TFA (121341-81-9 free base) TP508 TFA Others
TP508 TFA is a nonproteolytic thrombin peptide. TP508 TFA activates endothelial NO synthase (eNOS) and stimulates the production of NO in human endothelial cells. It activates endothelial cells and stem cells to revascul...
T62657 SHP504
SHP504 is an inhibitor of SHP2 phosphatase and acts on SHP21-525 (IC50: 21 μM).
T80132 CBP501 Affinity Peptide
CBP501 Affinity Peptide, a Chk kinase inhibitor, disrupts G2 arrest triggered by DNA-damaging agents and is utilized in cancer research [1].
T75763 TP508 TFA
TP508 TFA, a 23-amino acid segment of the thrombin molecule's receptor-binding domain, is a nonproteolytic thrombin peptide. It activates endothelial NO synthase (eNOS) to enhance nitric oxide (NO) production in human en...
T69846 VTP50469 mesylate
VTP-50469 is a novel, potent, selective, orally-available MeninMLL1 inhibitor, being effectively against MLL-rearranged and NPM1c+ leukemia, selectively killing cell lines with MLLrearrangements and NPM1c+ mutations.
T24736 RP5063 Hydrochloride RP-5063 HCl,RP 5063 HCl,RP 5063 Hydrochloride,RP-5063 Hydrochloride,RP5063 HCl
RP5063 Hydrochloride is a modulator of multimodal serotonin receptors.
TP1853 TP508
TP508 is a 23 amino acid synthetic peptide representing residues 508-530 of human prothrombin which is identified as a potential receptor-binding domain based on competition for high-affinity thrombin binding to fibrobla...
T69091 CBP501
CBP501 is a peptide with G2 checkpoint-abrogating activity. G2 checkpoint inhibitor CBP501 inhibits multiple serine/threonine kinases, including MAPKAP-K2, C-Tak1, and CHK1, that phosphorylate serine 216 of the dual-spec...
T72785 PRMT5:MEP50 PPI
PRMT5:MEP50 PPI, a pioneering inhibitor of the PRMT5:MEP50 protein-protein interaction (PRMT5:MEP50 PPI), demonstrates anti-tumor and anti-proliferative effects in lung and prostate cancer cells.
T13336L VTP50469 fumarate Others
VTP50469 fumarate is a highly selective and orally active inhibitor of Menin-MLL interaction (Ki: 104 pM), and has potently anti-leukemia activity.
T78846 EP12 Apoptosis
EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by disrupting the NF-κB signaling pathway, effectively inhibiting mult...
T38153 NF-κB Inhibitor (trifluoroacetate salt)
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells.1It blocks the...
T37559 NF-κB Control
NF-κB inhibitor is a synthetic peptide corresponding to the nuclear localization sequence (NLS) of NF-κB p105 subunit (also known as p50) appended to a hydrophobic sequence to facilitate import into living cells. It bloc...
Cat No. Product Name Synonyms Targets
TWS1977 Kamebakaurin Kamebakaurine NF-κB
1. Kamebakaurin (Kamebakaurine) has the ability to protect the liver from APAP-induced hepatotoxicity, presumably by both inhibiting the inflammatory response and oxidative stress. 2. Kamebakaurin inhibits the expression...
T3012 Mangiferin Alpizarin,Chinomin,Hedysarid Apoptosis , Others , NF-κB , Nrf2
Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.
TN3922 Effusanin E PARP , NF-κB , Caspase , COX , Antifection
Effusanin E shows antibacterial and anti-cancer activities, it significantly inhibits cell proliferation and induces apoptosis in NPC cells by suppressing p50/p65 proteins to down-regulate COX-2 expression .
TN4635 Neoechinulin A NADPH-oxidase , Beta Amyloid , ASK , IκB/IKK , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor
Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) ...

Natural Products

Kamebakaurin
TWS1977
Synonym: Kamebakaurine
Target: NF-κB
Mangiferin
T3012
Synonym: Alpizarin,Chinomin,Hedysarid
Target: Apoptosis, Others, NF-κB, Nrf2
Effusanin E
TN3922
Synonym:
Target: PARP, NF-κB, Caspase, COX, Antifection
Neoechinulin A
TN4635
Synonym:
Target: NADPH-oxidase, Beta Amyloid, ASK, IκB/IKK, p38 MAPK, TNF, NOS, NF-κB, COX, Prostaglandin Receptor

Recombinant Proteins

Species：
Human (6)
Mouse (6)
Expression System：
HEK293 Cells (9)
Baculovirus Insect Cells (2)
E. coli (1)
Tag：
C-His (2)
C-hFc (2)
His, Avi (2)
C-mFc (1)
C-rFc (1)
GST (1)
His, GST (1)
Tag Free (1)
hFc, Avi (1)
Cat No. Product Name Species Expression System
TMPY-01181 CD40 Protein, Human, Recombinant (His) Human HEK293 Cells
CD40 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is A0A0S2Z3C7.
TMPY-05957 CD40 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CD40 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.81 kDa and the accession number is P27512-1.
TMPY-03558 CDC37 Protein, Mouse, Recombinant Mouse Baculovirus Insect Cells
CDC37 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 44.7 kDa and the accession number is Q61081.
TMPY-03534 CDC37 Protein, Mouse, Recombinant (His & GST) Mouse Baculovirus Insect Cells
CDC37 Protein, Mouse, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 72.4 kDa and the accession number is Q61081.
TMPY-05614 CD40 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD40 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.4 kDa and the accession number is A0A0S2Z3C7.
TMPY-05359 CD40 Protein, Human, Recombinant (mFc) Human HEK293 Cells
CD40 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45.5 kDa and the accession number is NP_001309350.1.
TMPY-05599 CD40 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293 Cells
CD40 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 47.7 kDa and the accession number is A0A0S2Z3C7.
TMPY-00482 CD40 Protein, Human, Recombinant (hFc) Human HEK293 Cells
CD40 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is A0A0S2Z3C7.
TMPY-06024 CD40 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse HEK293 Cells
CD40 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.5 kDa and the accession number is P27512-1.
TMPY-05425 CD40 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
CD40 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.4 kDa and the accession number is P27512-1.
TMPY-04994 CD40 Protein, Mouse, Recombinant (rFc) Mouse HEK293 Cells
CD40 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P27512-1.
TMPY-02387 NF-kB p65 Protein, Human, Recombinant (aa 1-306, GST) Human E. coli
RELA (v-rel reticuloendotheliosis viral oncogene homolog A), also known as Nuclear factor NF-kappa-B p65 subunit, or Transcription factor p65, is a transcription factor expressed in growth plate chondrocytes where it fac...
Cat No. Product Name
L3800 NF-κB Signaling Compound Library

729 compounds
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening;

Libraries

NF-κB Signaling Compound Library
L3800
Compounds: 729
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