oxytetracycline

Oxytetracycline (Terramycin) is a TETRACYCLINE analog isolated from the actinomycete STREPTOMYCES rimosus and used in a wide variety of clinical conditions.

Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resulting in preventing peptide elongation and inhibiting protein synthesis.

4-Epioxytetracycline (Standard) is the standard substance of 4-Epioxytetracycline, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 4-Epioxytetracycline has a wide range of applications in life science related research.

Oxytetracycline-BSA is a hapten-carrier protein conjugate formed by coupling Oxytetracycline to bovine serum albumin (BSA). As a hapten, Oxytetracycline alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity. Oxytetracycline-BSA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M TBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

Oxytetracycline-OVA is a hapten-carrier protein conjugate formed by coupling Oxytetracycline to chicken ovalbumin (OVA). As a hapten, Oxytetracycline alone cannot induce an immune response and must be conjugated to a large molecular protein to become a complete antigen with immunogenicity.Oxytetracycline-OVA may be supplied as a lyophilized powder or as a solution. The solution is prepared in 0.01 M TBS (pH 7.4) buffer at a typical concentration of 1 mg/mL.

Oxytetracycline calcium, a tetracycline-class antibiotic, effectively inhibits both Gram-negative and Gram-positive bacteria. It acts as a protein synthesis inhibitor by preventing aminoacyl-tRNA binding to the m-ribosomal RNA complex and exhibits anti-HSV-1 activity [1] [2] [3].

Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.

Oxytetracycline Dihydrate (Standard) is the standard substance of Oxytetracycline Dihydrate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Oxytetracycline Dihydrate (Terramycin Dihydrate) is a prescription antibiotic, interfering with the ability of bacteria to produce essential proteins.

Oxytetracycline hydrochloride (Standard) is the standard substance of Oxytetracycline hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Oxytetracycline Hydrochloride (Dalimycin) is a tetracycline derivative produced by Streptomyces rimosus with antimicrobial activity. It interferes with the binding of aminoacyl-tRNA to the mRNA-ribosome complex, resulting in preventing peptide elongation and inhibiting protein synthesis.

α-Apooxytetracycline is a degradation product of Oxytetracycline, which belongs to the class of tetracycline antibiotics.

β-Apooxytetracycline is a potential impurity found in commercial preparations of oxytetracycline. β-Apooxytetracycline is a degradation product formed from oxytetracycline via acid hydrolysis. It has a relative potency of 0.1 compared with oxytetracycline for inhibiting the growth of aerobic sludge bacteria, an MIC50 value of 32 mg/L for tetracycline-sensitive strains of Pseudomonas, and MIC50 values of greater than 32 mg/L for tetracycline-sensitive strains of Agrobacterium, Moraxella, and Bacillus, as well as tetracycline-resistant strains of E. coli. β-Apooxytetracycline (10 mg/kg) is toxic to rats, decreasing body weight, disrupting blood cell counts, and inducing hepatocyte necrosis.

Doxycycline is an orally active tetracycline antibiotic with broad-spectrum inhibitory effects on matrix metalloproteinases (MMPs), possessing both antibacterial and antitumor activities, and is commonly used in inducible gene expression ON-OFF systems.

Sancycline is a semisynthetic tetracycline that inhibits protein translation by reversibly binding to the 30S ribosomal subunit and by blocking the entry of aminoacyl-tRNA into the ribosomal A site.

Sancycline is a semi-synthetic tetracycline antibiotic that is more active than tetracycline against 339 strains of anaerobic bacteria (MIC90s = 1 and 32 μg/ml, respectively).

2-Acetyl-2-decarboxamidotetracycline is a tetracycline-class antibiotic. It exhibits a UV absorption spectrum similar to that of tetracycline or 5-oxytetracycline at concentrations above 300 mμ, characteristic of the BCD ring system.

Oxytetracycline (OTC) is a broad-spectrum antibiotic that acts by inhibiting protein synthesis in bacteria. Oxytetracycline prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity[1][2][3