non-toxicity — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T2180	Hexythiazox		Parasite
	Hexythiazox is a mite growth regulator and a thiazolidine based acaricide that has long-lasting effects against many kinds of mites and is applied at any stage of the plant growth from budding to fruiting.		Parasite
TP2333	Cyclo(L-Pro-L-Tyr)		Others
	Maculosin is a secondary metabolite of fungi and bacteria.		Others
T3202	Fluensulfone	MCW-2	Parasite
	Fluensulfone (MCW-2) is a new nematicide of the fluoroalkenyl thioether group that has significantly reduced environmental impact with low toxicity to non-target insects and mammals.		Parasite
T39954	AU-15330		Epigenetic Reader Domain , PROTACs
	AU-15330 is a protein hydrolysis-targeted chimeric (PROTAC) degrader of the SWI/SNF ATPase subunits SMARCA2 and SMARCA4.AU-15330 potently inhibits tumor growth in a prostate cancer xenograft model and acts synergisticall...		Epigenetic Reader Domain , PROTACs
T37482	Diclofenac methyl ester		Others
	Diclofenac methyl ester is a hydrophobic prodrug form of the non-steroidal anti-inflammatory drug (NSAID) diclofenac . It is more soluble than diclofenac acid in isopropylmyristate. Diclofenac methyl ester does not perme...		Others
T19317	Ethyl phenylacetate		Others
	Ethyl phenylacetate is a “greener" solvent with low toxicity. Ethyl phenylacetate is a non-mutagenic and is a Kosher food additive. Ethyl phenylacetate gives the wines a strong honey-like character. Ethyl phenylacetate i...		Others
T6568	Licofelone	ML-3000	Apoptosis , Lipoxygenase , COX
	Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity ass...		Apoptosis , Lipoxygenase , COX
T22204	LY 2389575 hydrochloride		Beta Amyloid , GluR
	LY2389575 hydrochloride is an mGlu3 negative allosteric modulator (NAM) that is selective and non-competitive, with an IC50 value of 190 nM. LY2389575 hydrochloride induces an increase in the level of Mrc1, which amplifi...		Beta Amyloid , GluR
T6918	Olmutinib	HM61713, BI 1482694,BI 1482694,HM61713	EGFR , BTK
	Olmutinib (HM61713, BI 1482694) is an orally available small molecule, a mutant-selective inhibitor of epidermal growth factor receptor (EGFR) with potential antineoplastic activity. Olmutinib binds to and inhibits mutan...		EGFR , BTK
T21537L	TMC647055 Choline Hydroxide Salt	TMC647055 Choline Hydroxide Salt (1204416-97-6 free base)	HCV Protease
	TMC647055 Choline Hydroxide Salt is a novel and potent non-nucleoside inhibitor of the HCV NS5B polymerase which potentially for the treatment of HCV infection. It has nanomolar cellular potency (EC(50) of 82 nM) with mi...		HCV Protease
T3024	Avitinib	AC0010	EGFR , JAK , BTK
	Avitinib (AC0010), also known as AC0010 or AC0010MA, is an orally available, irreversible, epidermal growth factor receptor (EGFR) mutant-selective inhibitor, with potential antineoplastic activity. Upon oral administrat...		EGFR , JAK , BTK
T4776	Glycerol	Glycerin	Endogenous Metabolite
	Glycerol or glycerin is a colourless, odourless, viscous liquid that is sweet-tasting and mostly non-toxic. It is widely used in the food industry as a sweetener and humectant and in pharmaceutical formulations. Glycerol...		Endogenous Metabolite
T12615	(R)-Carvedilol	(R)-BM 14190	Others
	(R)-Carvedilol is a non-selective blocker of β/α-1. (R)-Carvedilol exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).		Others
T12794	(S)-Carvedilol	(S)-BM 14190	Others
	(S)-Carvedilol is a non-selective β/α-1 blocker.It exerts protection against the vascular or cardiac toxicity of Doxorubicin (DOX).		Others
TN3868	Dihydroxyaflavinine		GABA Receptor
	Dihydroxyaflavinine is a fungal toxin, it inhibits non-competitively GABAA receptor channel expressed in Xenopus oocytes.Dihydroxyaflavinine shows oral toxicity to the fall armyworm (Spodoptera frugiperda) and corn earwo...		GABA Receptor
T63517	BuChE-IN-4
	BuChE-IN-4 is a potent inhibitor of BuChE (IC50: 7.7 nM) and exhibits mild antioxidant capacity, non-toxicity, lipophilicity and neuroprotective effects.
T76217	Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2
	Ac-Val-Gln-aIle-Val-aTyr-Lys-NH2 demonstrates serum stability and non-toxicity to neuronal cells, while selectively inhibiting the fibrilization of tau in preference to Aβ 42.
TD0005	SYBR GREEN II	SUPER Green II RNA gel stain 10,000× concentrate in DMSO (Electrophoresis Grade)
	1) Non-toxicity: belong to flower-stem dye, easy to biodegrade, no carcinogenic toxicity. 2) High sensitivity: at least 100pg ssDNA or RNA can be detected, which is 25 ~ 100 times higher than EB staining. 3) High SIGNal-...
T62452	HIV-1 inhibitor-40
	HIV-1 inhibitor-40 (Compound 4ab) is an HIV-1 non-nucleoside reverse transcriptase inhibitor (NNRTI) (EC50: 1.9 nM) with no significant acute toxicity in vivo. Orexin receptor antagonist is a highly sensitive inhibitor o...
T3694L	Tebanicline tosylate
	Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine. Like epibatidine, tebanicline showed potent ...