n-acetyl-d-mannosamine

N-Acetyl-D-mannosamine (ManNAc) is a potential drug for treating hereditary inclusion body myopathy.

Cyclic N-Acetyl-D-mannosamine is a monosaccharide used as a precursor in the chemical or enzymatic synthesis of neuraminic acid found in glycolipids and glycoproteins.N-Acetyl-D-mannosamine is a specific substrate for the synthesis of n -acetylneuraminic acid, an essential precursor for bacterial podoplanar polysialic acid (PA).N-Acetyl-D-mannosamine is used in the synthesis of sialic acid. mannosamine is used in the synthesis of sialic acid. It is also an intermediate in the synthesis of many carbohydrate-derived bioactive compound families and drug candidates.N-Acetyl-D-mannosamine is used in the study of cognitive disorders and aging.

N-Acetylneuraminate lyase (CgNal) (Sialic acid aldolase (CgNal)), a class I aldolase frequently utilized in biochemical research, catalyzes the reversible condensation of pyruvate and N-acetyl-d-mannosamine (ManNAc), producing N-acetylneuraminic acid (Neu5Ac) [1].

Sialic acid aldolase (Pm NaNa) (EC 4.1.3.3) is a type I aldolase that catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (Neu5Ac) to produce pyruvate and N-acetyl-D-mannosamine (ManNAc), with the equilibrium favoring the cleavage of Neu5Ac.