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By Target- Vasopressin Receptor
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Results for "
mv1a
" in TargetMol Product Catalog- Inhibitors & Agonists3
Balovaptan
RG7314
T144941228088-30-9
Balovaptan (RG7314) is a highly potent and selective brain-penetrant vasopressin 1a (hV1a) receptor antagonist, with Kis of 1 and 39 nM for human (hV1a) and mouse (mV1a) receptors. It is used for the research of autism.
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V1a/V2 antagonist 1
T203525
V1a V2 antagonist 1 (Compound 18j) is an orally active dual-target antagonist of V1a and V2 receptors, exhibiting high binding affinity toward these receptors [Ki values are hV1a: 0.13 nM, hV2: 0.53 nM, and mV1a: 0.5 nM; IC50 for hV1a is 2.2 nM]. This compound can inhibit oxytocin-induced scratching behavior in mice.
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RG7713
RO 5028442
T4141920022-47-5
RG7713 (RO 5028442) has been used in trials studying Autistic Disorder.
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