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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2344 | LY 344864 | LY344864 | 5-HT Receptor |
LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor. | |||
T25616 | Lanepitant 2HCl | LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride | Neurokinin receptor |
Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflam... | |||
T76682 | Galcanezumab | LY 2951742 | CGRP Receptor |
Galcanezumab is a humanized IgG4 monoclonal antibody targeting the CGRP ligand, which binds to the ligand calcitonin gene-related peptide. Galcanezumab can be used to prevent and treat migraines or cluster headaches. | |||
T22346 | Indomethacin sodium hydrate | Indometacin sodium hydrate | COX |
Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX1/2 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries,... | |||
T26796 | BI-44370 | ||
BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain. | |||
T20917 | Lomerizine | ||
Lomerizine, a blocker of diphenylmethylpiperazine Ca2+ channel, is used to prevent migraines. | |||
T0216L | Eletriptan | UK-116,044-04 [as hydrobromide],UNII-22QOO9B8KI,UK-116,044,UK 116044 | |
Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug. | |||
T27196 | Donitriptan Mesylate | Donitriptan mesilate,F12640,F-12640,F 12640 | |
Donitriptan Mesylate, a 5-HT1B/1D agonist, is used potentially for the treatment of migraines. | |||
T71800 | Metoprolol HCl | ||
Metoprolol is a selective β1 receptor blocker medication. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. It is... | |||
T70837 | Rimegepant sulfate hydrate | ||
Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown ... | |||
T21558 | MK-3207 | ||
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep... |