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Search Results for " migraines "

11

Compounds

Cat No. Product Name Synonyms Targets
T2344 LY 344864 LY344864 5-HT Receptor
LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.
T25616 Lanepitant 2HCl LY303870 dihydrochloride,LY 303870 dihydrochloride,LY-303870 dihydrochloride,Lanepitant dihydrochloride Neurokinin receptor
Lanepitant 2HCl is a non-peptide neurokinin-1 receptor antagonist with analgesic and anti-inflammatory activity.Lanepitant 2HCl inhibits the binding of Substance P to the neurokinin-1 receptor, inhibits neurogenic inflam...
T76682 Galcanezumab LY 2951742 CGRP Receptor
Galcanezumab is a humanized IgG4 monoclonal antibody targeting the CGRP ligand, which binds to the ligand calcitonin gene-related peptide. Galcanezumab can be used to prevent and treat migraines or cluster headaches.
T22346 Indomethacin sodium hydrate Indometacin sodium hydrate COX
Indomethacin sodium hydrate (Indometacin sodium hydrate) is an orally active, competitive and reversible COX1/2 inhibitor with potential anti-inflammatory activity in induced migraines, induced gastrointestinal injuries,...
T26796 BI-44370
BI-44370, a CGRP (calcitonin gene-related peptide) receptor antagonist, can be used to treat migraines and other chronic pain.
T20917 Lomerizine
Lomerizine, a blocker of diphenylmethylpiperazine Ca2+ channel, is used to prevent migraines.
T0216L Eletriptan UK-116,044-04 [as hydrobromide],UNII-22QOO9B8KI,UK-116,044,UK 116044
Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.
T27196 Donitriptan Mesylate Donitriptan mesilate,F12640,F-12640,F 12640
Donitriptan Mesylate, a 5-HT1B/1D agonist, is used potentially for the treatment of migraines.
T71800 Metoprolol HCl
Metoprolol is a selective β1 receptor blocker medication. It is used to treat high blood pressure, chest pain due to poor blood flow to the heart, and a number of conditions involving an abnormally fast heart rate. It is...
T70837 Rimegepant sulfate hydrate
Rimegepant, also known as BMS-927711 and BHV-3000, is a potent, selective, competitive, and orally active calcitonin gene-related peptide (CGRP) antagonist in clinical trials for treating migraines. Rimegepant has shown ...
T21558 MK-3207
MK-3207 is a potent and orally bioavailable CGRP receptor antagonist (IC 50 = 0.12 nM; K i = 0.024 nM); highly selective versus human AM1, AM2, CTR, and AMY3. IC50 Value: 0.024 nM (Ki, Human CGRP) [1] As other CGRP recep...
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