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mb468

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
INH154
T116571587705-63-2
INH154 is a highly potent inhibitor of Nek2 and Hec1 binding (INH), with IC50 values of 120 nM in MB468 cells and 200 nM in Hela cells.
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CNBCA
T79311
CNBCA, a selective and potent competitive inhibitor of the SHP2 enzyme, exhibits an IC50 value of 0.87 μM. It binds to the full-length SHP2, effectively inhibiting its enzyme activity, as well as impeding pAkt and pERK1 2. Furthermore, CNBCA suppresses the proliferation of BT474 and MDA-MB468 cells, indicating potential utility in breast cancer research [1].
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INH6
T61801001753-24-7
INH6, an effective Hec1 inhibitor, selectively disrupts the Hec1 Nek2 interaction and induces chromosome mis-alignment.
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