mage-a3

This peptide MAGE-3-encoded HLA-A24 epitope is a high MHC binder.The identification of this MAGE-3/HLA-A24 peptide may as a result effectiveially offer the opportunities to design peptide-based immunotherapeutic approaches that might prove to be potent in

Anti-MAGEA3 Antibody is a humanized anti-MAGEA3 antibody expressed by CHO cells. Anti-MAGEA3 Antibody can be used for activity assays, functional studies, binding affinity analysis, and other applications, serving as an essential tool in biological research.

KL-465, a MAGE-A3 PROTAC degrader, effectively degrades MAGE-A3 in HeLa cells with a DC50 of 2 μM. It also inhibits the proliferation of MAGE-A3-positive cancer cells, specifically in HCT116, A375, and HeLa cell lines.

KL 465 is a degrader of MAGE-A3. The degradation of MAGE-A3 caused by KL 465 leads to reduced viability of cancer cells, and this effect is dependent on the VHL protein.

MAGE-3 Antigen (167-176) (human) is an eight-amino-acid polypeptide epitope for HLA-B44 molecules, encoded by the melanoma antigen gene (MAGE) [1].