m-140

ISAM-140 is a potent and highly selective antagonist of A2B adenosine receptor.

M 140 is a bioactive chemical.

Lortalamine is an antidepressant which was synthesized in the early 1980s. It acts as a potent and highly selective norepinephrine reuptake inhibitor.

EM 1404 is a 17β-HSD5 inhibitor with an IC50 value of 3.2 nM.

Isoxsuprine hydrochloride (Standard) is the standard substance of Isoxsuprine hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Isoxsuprine hydrochloride (Isolait) is a beta-adrenergic agonist that causes direct relaxation of uterine and vascular smooth muscle.

Josamycin (Standard) is the standard substance of Josamycin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Josamycin (EN-141) is a macrolide antibiotic exhibiting antimicrobial activity. The dissociation constant Kd from ribosome for Josamycin is 5.5 nM.

Kanamycin sulfate (Standard) is the standard substance of Kanamycin sulfate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kanamycin sulfate (Kanamycin monosulfate) is an aminoglycoside antibiotic that interferes with protein synthesis by binding to the 70S ribosomal subunit of bacteria. Kanamycin sulfate exhibits antimicrobial activity against both Gram-positive and Gram-negative bacteria, as well as mycoplasmas.

Kasugamycin hydrochloride (Standard) is the standard substance of Kasugamycin hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Kasugamycin hydrochloride (Kasumin) is an aminoglycoside antibiotic that was originally isolated in 1965, from Streptomyces kasugaensis, a Streptomyces strain found near the Kasuga shrine in Nara, Japan. Kasugamycin hydrochloride was discovered by Hamao Umezawa, who also discovered kanamycin and bleomycin, as a drug which could prevent growth of a fungus causing rice blast disease.

Grayanotoxin I (Standard) is a reference standard for research and analysis in studies involving Grayanotoxin I. Grayanotoxin I is a natural product for research related to life sciences. The catalog number is TN4165 and the CAS number is 4720-09-6.

Ketoconazole (Standard) is the standard substance of Ketoconazole, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ketoconazole (R-41400), a CYP3A4 inhibitor, is an imidazole anti-fungal agent.

Farrerol (Standard) is a reference standard for research and analysis in studies involving Farrerol. 1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3. Farrerol inactivates KEAP-1 or activates the Akt, p38 and ERK to facilitate the release of Nrf2 from Keap1 and subsequent reduces the intracellular production of reactive oxygen species via the induction of HO-1 expression. 4. Farrerol has protective effects against H2O2-induced apoptosis in EA.hy926 cells, and suggests that Farrerol is a potential candidate for the intervention of endothelial-injury-associated cardiovascular diseases.

Ketoprofen (Standard) is the standard substance of Ketoprofen, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ketoprofen (RP-19583) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic and antipyretic effects. Ketoprofen inhibits the activity of the enzymes cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. The resulting decrease in prostaglandin synthesis, by prostaglandin synthase, is responsible for the therapeutic effects of ibuprofen. Ketoprofen also causes a decrease in the formation of thromboxane A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

Dulcoside A (Standard) is a reference standard for research and analysis in studies involving Dulcoside A. Dulcoside A is isolated from Stevia rebaudiana. Dulcoside A is a sweetener and has antioxidant activity.

Ketotifen fumarate (Standard) is the standard substance of Ketotifen fumarate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.