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Search Results for " lymphocyte "

Targets

78

Compounds

14

Natural Products

435

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T9919 Alemtuzumab Others
Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.
T3258 Ponesimod ACT-128800 S1P Receptor , LPL Receptor
Ponesimod (ACT-128800) is an orally available sphingosine-1-phosphate receptor 1 (S1PR1, S1P1) agonist with potential immunomodulating activity.
TP2412 Tanurmotide Human lymphocyte antigen 6k-(101-111)-peptide.,Arg-tyr-cys-asn-leu-glu-gly-pro-pro-ile
Tanurmotide is a bioactive chemical.
T9616 PD-1/PD-L1-IN-10 PD-1/PD-L1
PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.
T5097 Ezatiostat TER199(free base),TLK199 Apoptosis , Glutathione Peroxidase , GST
Ezatiostat (TER199(free base)) is a tripeptide analog of glutathione that can selectively inhibit GSTP1-1 catalytic activity.
T22776 Ezatiostat hydrochloride TLK199 HCl,TER199 Glutathione Peroxidase
Ezatiostat hydrochloride (TLK199 HCl) is an effective inhibitor of glutathione S-transferase. Ezatiostat hydrochloride is a novel glutathione analog and the potential treatment of cytopenias. In addition, Ezatiostat hydr...
T3977 Lifitegrast SHP-606,SAR 1118 Integrin
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
T10389L Aspartyl-alanyl-diketopiperazine acetate DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base) Others
Aspartyl-alanyl-diketopiperazine acetate (DA-DKP) (DA-DKP) can modulate the inflammatory immune response through a molecular pathway implicated in T- lymphocyte anergy.
T9925 Ofatumumab Others
Ofatumumab is a fully human monoclonal antibody to CD20 which appears to inhibit early-stage B lymphocyte activation
T12783 RWJ 50271 Integrin
RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 μM in HL60 cells).
T77466 Tremelimumab Ticilimumab,CP-675206 Others
Tremelimumab is a cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4) blocking antibody.Tremelimumab is often used in combination with Durvalumab for the treatment of solid cancers such as hepatocellular carcinoma and l...
TQ0007 Cintirorgon LYC-55716 ROR
Cintirorgon (LYC-55716) is a selective, oral agonist of RORγ. Cintirorgon modulates gene expression of RORγ expressing T lymphocyte immune cells.
T72528 NSC243928 mesylate HuR
NSC243928 mesylate binds to human lymphocyte antigen 6 (LY6), a cell growth inhibitor with anticancer activity, and induces cell death in triple-negative breast cancer cells in a LY6K-dependent manner.
TP1076L AUNP-12 acetate AUNP-12 acetate (1353563-85-5 Free base) PD-1/PD-L1
AUNP-12 acetate is a polypeptide inhibitor of PD-1 that is equivalent to PD-1 and PD-2 in inhibiting lymphocyte proliferation and effector fuction, in addition to immune activation and antitumor activity.
T0944 Levamisole hydrochloride (-)-Tetramisole hydrochloride Phospholipase , AChR , Parasite , HSV
Levamisole hydrochloride ((-)-Tetramisole hydrochloride) is an antihelminthic drug that has been tried experimentally in rheumatic disorders where it apparently restores the immune response by increasing macrophage chemo...
T3614 Inosine pranobex Groprinosin,Isoprinosine,Immunovir,Delimmun IL Receptor , HIV Protease
Inosine pranobex (Delimmun) has a number of immunomodulatory effects, including inducing T-lymphocyte differentiation, augmenting macrophage and NK cell functions, and stimulating IL-2 production. Through these effects a...
TQ0291 Firategrast SB 683699 Integrin
Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous system (CNS) and decreases multiple sclerosis (MS) activity...
T63790 Cbl-b-IN-3 E1/E2/E3 Enzyme
Cbl-b-IN-3 is a potent proto-oncogene-B (CPL-B) inhibitor of casitas B-series lymphoma (ic50 < 1 nM). Cpl-b, a cyclic E3 ubiquitin protein ligase, is involved in the setting of T lymphocyte activation thresholds. Cpl-b n...
T3626 Acalabrutinib ACP-196 BTK
Acalabrutinib (ACP-196), also known as ACP-196, is an orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. Upon administration, ACP-196 inhibits the activity of BTK and pre...
T28708 Sch 24937
Sch 24937 is a potent immunosuppressant on B lymphocyte mediated immune responses.
T70253 Nordimaprit
Nordimaprit is effective agonist in the inhibition of lymphocyte activation.
TP2336 Tripalmitoyl pentapeptide P3C-Ssna,Bpppcssaa,Bppp cssaa,Bppp-cssaa,P3C Ssna P3CSsna
Tripalmitoyl pentapeptide is a Mitogen from E Coli lipoprotein. It also is a potent macrophage B lymphocyte activator.
T26836 BLL5 Maleate
BLL5 Maleate is a first-in-class selective PRMT5 inhibitor, it blocks EBV-driven B lymphocyte transformation and survival while leaving normal B cells unaffected.
T26752 BC12 BC 12,BC-12
BC12 exhibits unusually potent immunomodulatory actions on T lymphocyte function, including inhibition of T cell proliferation and IL-2 cytokine production.
T70944 Carotegrast methyl HCl
Carotegrast methyl, also known as AJM300 and PTC-100, is an orally-active small molecule that antagonises the α4 integrin receptor. AJM300 reduces inflammation by blocking leucocyte trafficking. Oral treatment with AJM30...
T78309 Telitacicept RC18
Telitacicept (RC18), a fully human TACI-Fc fusion protein, acts as a dual inhibitor of B lymphocyte stimulator (BLyS) and APRIL (a proliferation-inducing ligand), effectively impeding B lymphocyte proliferation. This com...
T68349 Lck inhibitor II
Lck inhibitor II is a cell-permeable, ATP binding site-targeting, tri-substituted pyrimidine that acts as a highly potent Lck (lymphocyte specific kinase) inhibitor
T28221 NVP-QAV-680 NVP-QAV680,QAV690 free acid,NVP,QAV-690 free acid,NVPQAV680,QAV 690 free acid
NVP-QAV-680 is a potent and selective antagonist of CRTh2 receptor. NVP-QAV-680 has nM functional potency for inhibition of CRTh2 driven human eosinophil and Th2 lymphocyte activation in vitro.
T14558 BI-1950 Integrin
BI-1950 is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor and the LFA-1 is an essential component in normal immune system function and a target for drug discovery[1].
TP1612 OVA sequence (323-336) OVA sequence 323-336
This peptide is a cognate helper T-lymphocyte peptide that is employed to enhance CTL epitope immunogencity
T15337 Forodesine BCX-1777,Immucillin-H Others
Forodesine is a potent human lymphocyte proliferation inhibitor. Forodesine is an orally active inhibitor of purine nucleoside phosphorylase (IC50s: 0.48 to 1.57 nM for human, mouse, rat, monkey, and dog PNP). It could i...
T27368 FR 901235 FR901235,FR-901235
FR-901235 is an immunoactive substance produced by an imperfect fungus, Paecilomyces carneus F-4882. FR-901235 restores the mitogen-induced lymphocyte proliferation to a normal level, which has been suppressed by additio...
T8888 Lck-IN-1
Lck-IN-1 is a potent inhibitor of lymphocyte protein tyrosine kinase (Lck) [1].
T81627 Oberotatug
Oberotatug is a human IgG1κ monoclonal antibody that specifically targets the lymphocyte antigen LY75 (CD205) [1].
T37675 3-Deaza-2'-deoxyadenosine
3-Deaza-2'-deoxyadenosine strongly inhibits lymphocyte-mediated cytolysis with low cytotoxicity when applied at 100 μM. This nucleoside can also be used to evaluate the role of the adenine N3 nitrogen in DNA structure an...
T3977L Lifitegrast sodium SAR-1118-023,SAR1118-023,SAR 1118-023,Xiidra
Lifitegrast sodium (SAR-1118) is an LFA-1 antagonist for the therapy of vascular complications of the eye. It inhibits T cell-mediated inflammation by blocking the binding of two cell surface proteins (lymphocyte functio...
T82449 Eramkafusp Alfa
Eramkafusp alfa is a human IgG1 antibody that targets the murine B lymphocyte antigen CD20, also known as MS4A1 [1].
TP1030 Thymus factor X TFX-Jelfa
Thymic factor X (TFX-Jelfa) is an aqueous extract from the thymus of a juvenile calf and is a natural stimulator of lymphocyte function.
T38386 Drimentine C
Drimentine C is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It inhibits proliferation of NS-1 murine β lymphocyte myeloma cells by 63 and 98% in vitro when used at concentra...
TP1515 HPV16-E711-20 epitope
HPV16-E711-20 epitope is a well-known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of the HPV16 E7 protein that shows high-affinity binding to HLA-A2 in vitro.
T39292 NS2 (114-121), Influenza NS2 (114-121), Influenza
NS2 (114-121), Influenza, is a fragment derived from the nonstructural protein 2 (NS2) of the influenza virus. This compound serves as an epitope for influenza research and can be utilized to study the CD8+ cytotoxic T l...
T28838 SPM-242 SPM 242
SPM-242 is an orthosteric agonist of Sphingosine 1-phosphate (S1P) and a bitopic antagonist. S1P is a lysophospholipid signaling molecule that regulates important biological functions, including vascular development and...
T77103 Nurulimab
Nurulimab (BCD-145) is an anti- cytotoxic T lymphocyte antigen-4 (anti-CTLA-4) humanized monoclonal antibody. Nurulimab can be can be used in research of melanoma [1] .
T78298 Alefacept LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273
Alefacept (BG 9273), a fusion protein combining human lymphocyte function-associated antigen 3 with immunoglobulin 1, is utilized in the research of chronic plaque psoriasis [1].
T38227 Quin C1
Potent and selective FPR2 agonist (EC50 = 15 nM). Induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts ...
T11313 Forodesine hydrochloride BCX-1777 hydrochloride,Immucillin-H hydrochloride Others
Forodesine hydrochloride is a potent human lymphocyte proliferation inhibitor. Forodesine hydrochloride could induce apoptosis in leukemic cells by increasing the dGTP levels. Forodesine hydrochloride (BCX-1777 hydrochlo...
T80573 Firastotug
Firastotug, an IgG1κ antibody, targets CTLA4, a cytotoxic T lymphocyte-associated protein that serves as a crucial immune checkpoint in autoimmunity and cancer [1].
T79816 S1P1 agonist 6 LPL Receptor
Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive agent in autoimmune disease research [1].
T35736 Drimentine B
Drimentine B is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria. It is active against Gram-positive and Gram-negative bacteria, fungi, and yeast, and has anthelmintic properties....
T82743 CFP10 (71–85)
CFP10 (71–85) is an immunologically active peptide that induces IFN-γ production and cytotoxic T lymphocyte (CTL) activity in CD4+ and CD8+ T cells from individuals with diverse MHC class II and I expression profiles.

Compounds

Alemtuzumab
T9919
Synonym:
Target: Others
Ponesimod
T3258
Synonym: ACT-128800
Target: S1P Receptor, LPL Receptor
Tanurmotide
TP2412
Synonym: Human lymphocyte antigen 6k-(101-111)-peptide.,Arg-tyr-cys-asn-leu-glu-gly-pro-pro-ile
Target:
PD-1/PD-L1-IN-10
T9616
Synonym:
Target: PD-1/PD-L1
Ezatiostat
T5097
Synonym: TER199(free base),TLK199
Target: Apoptosis, Glutathione Peroxidase, GST
Ezatiostat hydrochloride
T22776
Synonym: TLK199 HCl,TER199
Target: Glutathione Peroxidase
Lifitegrast
T3977
Synonym: SHP-606,SAR 1118
Target: Integrin
Aspartyl-alanyl-diketopiperazine acetate
T10389L
Synonym: DA-DKP,Aspartyl-alanyl-diketopiperazine acetate(110954-19-3 Free base)
Target: Others
Ofatumumab
T9925
Synonym:
Target: Others
RWJ 50271
T12783
Synonym:
Target: Integrin
Tremelimumab
T77466
Synonym: Ticilimumab,CP-675206
Target: Others
Cintirorgon
TQ0007
Synonym: LYC-55716
Target: ROR
NSC243928 mesylate
T72528
Synonym:
Target: HuR
AUNP-12 acetate
TP1076L
Synonym: AUNP-12 acetate (1353563-85-5 Free base)
Target: PD-1/PD-L1
Levamisole hydrochloride
T0944
Synonym: (-)-Tetramisole hydrochloride
Target: Phospholipase, AChR, Parasite, HSV
Inosine pranobex
T3614
Synonym: Groprinosin,Isoprinosine,Immunovir,Delimmun
Target: IL Receptor, HIV Protease
Firategrast
TQ0291
Synonym: SB 683699
Target: Integrin
Cbl-b-IN-3
T63790
Synonym:
Target: E1/E2/E3 Enzyme
Acalabrutinib
T3626
Synonym: ACP-196
Target: BTK
Sch 24937
T28708
Synonym:
Target:
Nordimaprit
T70253
Synonym:
Target:
Tripalmitoyl pentapeptide
TP2336
Synonym: P3C-Ssna,Bpppcssaa,Bppp cssaa,Bppp-cssaa,P3C Ssna P3CSsna
Target:
BLL5 Maleate
T26836
Synonym:
Target:
BC12
T26752
Synonym: BC 12,BC-12
Target:
Carotegrast methyl HCl
T70944
Synonym:
Target:
Telitacicept
T78309
Synonym: RC18
Target:
Lck inhibitor II
T68349
Synonym:
Target:
NVP-QAV-680
T28221
Synonym: NVP-QAV680,QAV690 free acid,NVP,QAV-690 free acid,NVPQAV680,QAV 690 free acid
Target:
BI-1950
T14558
Synonym:
Target: Integrin
OVA sequence (323-336)
TP1612
Synonym: OVA sequence 323-336
Target:
Forodesine
T15337
Synonym: BCX-1777,Immucillin-H
Target: Others
FR 901235
T27368
Synonym: FR901235,FR-901235
Target:
Lck-IN-1
T8888
Synonym:
Target:
Oberotatug
T81627
Synonym:
Target:
3-Deaza-2'-deoxyadenosine
T37675
Synonym:
Target:
Lifitegrast sodium
T3977L
Synonym: SAR-1118-023,SAR1118-023,SAR 1118-023,Xiidra
Target:
Eramkafusp Alfa
T82449
Synonym:
Target:
Thymus factor X
TP1030
Synonym: TFX-Jelfa
Target:
Drimentine C
T38386
Synonym:
Target:
HPV16-E711-20 epitope
TP1515
Synonym:
Target:
NS2 (114-121), Influenza
T39292
Synonym: NS2 (114-121), Influenza
Target:
SPM-242
T28838
Synonym: SPM 242
Target:
Nurulimab
T77103
Synonym:
Target:
Alefacept
T78298
Synonym: LFA 3TIP,Human LFA 3IgG fusion protein,BG 9273
Target:
Quin C1
T38227
Synonym:
Target:
Forodesine hydrochloride
T11313
Synonym: BCX-1777 hydrochloride,Immucillin-H hydrochloride
Target: Others
Firastotug
T80573
Synonym:
Target:
S1P1 agonist 6
T79816
Synonym:
Target: LPL Receptor
Drimentine B
T35736
Synonym:
Target:
CFP10 (71–85)
T82743
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
T7981 2-Fluoroadenosine Others
2-Fluoroadenosine is a potent inhibitor of lymphocyte-mediated cytolysis.
TN2283 Tripterifordin HIV Protease
Tripterifordin shows anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 1 microgram/ml.
T10117 3'-​O-​Acetylhamaudol Others
3'- O- Acetylhamaudol, isolated from the roots of Angelica japonica, exhibits anti-tumor activity through dual actions, anti-angiogenesis and intestinal intraepithelial lymphocyte activation.
TN1443 Biorobin Kaempferol 3-O-robinobioside
Biorobin (Kaempferol 3-O-robinobioside), a flavonoid from the Euphorbiaceae plant tropical iron amaranth, significantly inhibits human lymphocyte proliferation in vitro.
T3S1513 (20R)-Protopanaxadiol Protopanaxadiol,20R-Protopanaxadiol,(20R)-Protopanaxdiol Others , Antibacterial
1. (20R)-Protopanaxadiol ((20R)-Protopanaxdiol) has the effect of anti-tumor through increasing the activity of body immunity, inhibiting tumor interstitial microvascular density and its proliferation activity, improving...
T3S0364 L-Arginine L-Arg,(S)-(+)-Arginine IL Receptor , Endogenous Metabolite , NO Synthase
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate...
T1257 Bestatin Ubenimex Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin...
T20879 Tacrolimus monohydrate FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,FK 506 Phosphatase , Others , Antibacterial , Antibiotic , Autophagy
Tacrolimus monohydrate (LCP-Tacro) is a macrolide from the culture broth of a strain of Streptomyces tsukubaensis, binds to FK506 binding protein (FKBP) to form a complex. Tacrolimus inhibits calcineurin phosphatase, whi...
T5S0106 Peimisine Ebeiensine RAAS , AChR
1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Pe...
T81735 Mycestericin C
Mycestericin C, isolated from Mycelia sterilia ATCC 20349 culture broth, inhibits lymphocyte proliferation in the mouse allogeneic mixed lymphocyte reaction [1].
TN4934 Salaspermic acid HIV Protease
Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.
TN2116 Pteropodine BCL , Calcium Channel , 5-HT Receptor
Pteropodine acts as a positive modulator of muscarinic M(1) and 5-HT(2) receptors. Pteropodine shows antigenotoxic, antioxidant and lymphocyte induction effects, it also shows strong apoptotic effect on acute leukaemic l...
TN4646 Neotripterifordin HIV Protease
Neotripterifordin shows potent anti-HIV replication activity in H9 lymphocyte cells with an EC50 of 25 nM and TI of 125.
TN1194 16beta,17-Dihydroxy-ent-kaurane-19-oic acid HIV Protease
16beta,17-Dihydroxy-ent-kaurane-19-oic acid as an anti-HIV principle, it showed significant activity against HIV replication in H9 lymphocyte cells with an EC50 value of 0.8 microgram/mL. It also possesses the activities...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-05092 LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His) Cynomolgus HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04730 LAG-3 Protein, Human, Recombinant (His) Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04939 LAG-3 Protein, Human, Recombinant Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-00369 LY6D Protein, Human, Recombinant (mFc) Human HEK293
LY6D (Lymphocyte Antigen 6 Family Member D) is a Protein Coding gene. It may act as a specification marker at the earliest stage specification of lymphocytes between B- and T-cell development. Marks the earliest stage of...
TMPY-01604 CTLA-4 Protein, Mouse, Recombinant (His) Mouse HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-00322 DEC-205 Protein, Human, Recombinant (His) Human HEK293
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-05159 Granzyme A/GZMA Protein, Human, Recombinant (His) Human HEK293
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His) Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPJ-01172 IL-17 Protein, Mouse, Recombinant (His) Mouse Human Cells
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid seque...
TMPY-04824 CTLA-4 Protein, Human, Recombinant Human HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPJ-00035 IL-4 Protein, Human, Recombinant (His) Human Human Cells
Interleukin-4 (IL-4) is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. IL-4 is produced by mast cells, T cells, and bone marrow stromal ce...
TMPY-00461 BTLA Protein, Rat, Recombinant (mFc) Rat HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-03759 LAG-3 Protein, Rat, Recombinant (His) Rat HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-03359 CTLA-4 Protein, Cynomolgus, Rhesus, Recombinant (hFc) Cynomolgus,Rhesus HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-02411 CTLA-4 Protein, Canine, Recombinant (His) Canine HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-00620 CTLA-4 Protein, Canine, Recombinant (hFc) Canine HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-03589 CTLA4 Protein, Cynomolgus/Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-05101 BTLA Protein, Rhesus, Recombinant (His) Rhesus HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-04047 BTLA Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPJ-01391 BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) Mouse Human Cells
TNFSF13B/TNFSF20 belongs to the tumor necrosis factor family. It abundantly is expressed in peripheral blood Leukocytes and is specifically expressed in monocytes and macrophages. Also found in the spleen, lymph node, bo...
TMPJ-00129 BTLA Protein, Human, Recombinant (His) Human Human Cells
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed...
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His) Human HEK293
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-02492 CTLA-4 Protein, Rat, Recombinant (hFc) Rat HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-03186 BTLA Protein, Mouse, Recombinant (hFc) Mouse HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPJ-00709 LY6H Protein, Human, Recombinant (His) Human Human Cells
Lymphocyte Antigen 6H (LY6H) is a novel member of the LY6 family of glycosylphosphatidylinositol-anchored cell surface glycoproteins. LY6H contains one UPAR/Ly6 domain. Human LY6H is synthesized as a 140 amino acid precu...
TMPY-02557 CTLA-4 Protein, Rat, Recombinant (His) Rat HEK293
Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands o...
TMPY-06923 BTLA Protein, Mouse, Recombinant (His) Mouse HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) Mouse Human Cells
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes....
TMPY-00878 MD1 Protein, Mouse, Recombinant (His) Mouse HEK293
MD-1 and MD-2 are secretory glycoproteins that exist on the cell surface in complexes with transmembrane proteins. MD-1 is anchored by radioprotective 15 (RP15) which is a molecule containing leucine-rich repeats and is ...
TMPJ-00420 CTLA-4 Protein, Mouse, Recombinant (Flag) Mouse Human Cells
Mouse Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule. Within the ECD, Mouse CTLA-4 shares 68% aa sequence identity with human. CTLA4 is similar to the T cell costimulatory pro...
TMPJ-00108 CTLA-4 Protein, Human, Recombinant (GST) Human Human Cells
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence...
TMPY-00517 LSP1 Protein, Human, Recombinant (His) Human HEK293
LSP1 (Lymphocyte Specific Protein 1) is a Protein Coding gene. This gene encodes an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regula...
TMPY-05130 LAG-3 Protein, Human, Recombinant, Biotinylated Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPJ-00635 CTLA-4 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus Human Cells
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPJ-00636 CTLA-4 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPJ-00640 CTLA-4 Protein, Cavia porcellus, Recombinant (His) Cavia porcellus P. pastoris
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily.CD28 and CTLA-4, together with their ligands, B7-1 and B7-2, constitute one of the domina...
TMPY-06913 BTLA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-00175 BTLA Protein, Human, Recombinant (hFc) Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-06922 BTLA Protein, Human, Recombinant (isoform1, His) Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPJ-00107 CTLA-4 Protein, Human, Recombinant (Flag) Human Human Cells
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA encodes 223 amino acids (aa) including a 35 aa signal sequence...
TMPY-03999 MD2/LY96 Protein, Mouse, Recombinant (hFc) Mouse HEK293
LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell su...
TMPY-04528 LAG-3 Protein, Human, Recombinant (hFc) Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-06829 BTLA Protein, Human, Recombinant (isoform 1,mFc) Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-06931 LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-04731 LAG-3 Protein, Human, Recombinant (mFc) Human HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
TMPY-06930 BTLA Protein, Human, Recombinant (isoform1,hFc) Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-05416 BTLA Protein, Human, Recombinant (hFc & Avi), Biotinylated Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPY-05828 BTLA Protein, Human, Recombinant (mFc) Human HEK293
BTLA is a inhibitory molecule which belongs to the Ig superfamily. It down-modulates immune responses. As such, reagents that regulate the binding of BTLA to its ligand or alter BTLA signaling have significant therapeuti...
TMPJ-00329 CD19 Protein, Rhesus macaque, Recombinant (hFc) Rhesus macaque Human Cells
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recog...
TMPY-04611 LAG-3 Protein, Mouse, Recombinant (hFc) Mouse HEK293
LAG3 (Lymphocyte Activating 3) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. LAG3, also known as CD223 and Lymphocyte activation gene 3, belongs to the immunoglobulin (Ig) superfami...
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LAG-3 Protein, Cynomolgus, Recombinant (74 Pro, His)
TMPY-05092
Species: Cynomolgus
Expression System: HEK293
LAG-3 Protein, Human, Recombinant (His)
TMPY-04730
Species: Human
Expression System: HEK293
LAG-3 Protein, Human, Recombinant
TMPY-04939
Species: Human
Expression System: HEK293
LY6D Protein, Human, Recombinant (mFc)
TMPY-00369
Species: Human
Expression System: HEK293
CTLA-4 Protein, Mouse, Recombinant (His)
TMPY-01604
Species: Mouse
Expression System: HEK293
DEC-205 Protein, Human, Recombinant (His)
TMPY-00322
Species: Human
Expression System: HEK293
Granzyme A/GZMA Protein, Human, Recombinant (His)
TMPY-05159
Species: Human
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant (His)
TMPY-04348
Species: Human
Expression System: HEK293
IL-17 Protein, Mouse, Recombinant (His)
TMPJ-01172
Species: Mouse
Expression System: Human Cells
CTLA-4 Protein, Human, Recombinant
TMPY-04824
Species: Human
Expression System: HEK293
IL-4 Protein, Human, Recombinant (His)
TMPJ-00035
Species: Human
Expression System: Human Cells
BTLA Protein, Rat, Recombinant (mFc)
TMPY-00461
Species: Rat
Expression System: HEK293
LAG-3 Protein, Rat, Recombinant (His)
TMPY-03759
Species: Rat
Expression System: HEK293
CTLA-4 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
TMPY-03359
Species: Cynomolgus,Rhesus
Expression System: HEK293
CTLA-4 Protein, Canine, Recombinant (His)
TMPY-02411
Species: Canine
Expression System: HEK293
CTLA-4 Protein, Canine, Recombinant (hFc)
TMPY-00620
Species: Canine
Expression System: HEK293
CTLA4 Protein, Cynomolgus/Rhesus, Recombinant (His)
TMPY-03589
Species: Cynomolgus,Rhesus
Expression System: HEK293
BTLA Protein, Rhesus, Recombinant (His)
TMPY-05101
Species: Rhesus
Expression System: HEK293
BTLA Protein, Rhesus, Recombinant (hFc)
TMPY-04047
Species: Rhesus
Expression System: HEK293
BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
TMPJ-01391
Species: Mouse
Expression System: Human Cells
BTLA Protein, Human, Recombinant (His)
TMPJ-00129
Species: Human
Expression System: Human Cells
Granzyme B/GZMB Protein, Human, Recombinant (His)
TMPY-00817
Species: Human
Expression System: HEK293
CTLA-4 Protein, Rat, Recombinant (hFc)
TMPY-02492
Species: Rat
Expression System: HEK293
BTLA Protein, Mouse, Recombinant (hFc)
TMPY-03186
Species: Mouse
Expression System: HEK293
LY6H Protein, Human, Recombinant (His)
TMPJ-00709
Species: Human
Expression System: Human Cells
CTLA-4 Protein, Rat, Recombinant (His)
TMPY-02557
Species: Rat
Expression System: HEK293
BTLA Protein, Mouse, Recombinant (His)
TMPY-06923
Species: Mouse
Expression System: HEK293
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
TMPJ-00850
Species: Mouse
Expression System: Human Cells
MD1 Protein, Mouse, Recombinant (His)
TMPY-00878
Species: Mouse
Expression System: HEK293
CTLA-4 Protein, Mouse, Recombinant (Flag)
TMPJ-00420
Species: Mouse
Expression System: Human Cells
CTLA-4 Protein, Human, Recombinant (GST)
TMPJ-00108
Species: Human
Expression System: Human Cells
LSP1 Protein, Human, Recombinant (His)
TMPY-00517
Species: Human
Expression System: HEK293
LAG-3 Protein, Human, Recombinant, Biotinylated
TMPY-05130
Species: Human
Expression System: HEK293
CTLA-4 Protein, Cynomolgus, Recombinant (hFc)
TMPJ-00635
Species: Cynomolgus
Expression System: Human Cells
CTLA-4 Protein, Cynomolgus, Recombinant (His)
TMPJ-00636
Species: Cynomolgus
Expression System: Human Cells
CTLA-4 Protein, Cavia porcellus, Recombinant (His)
TMPJ-00640
Species: Cavia porcellus
Expression System: P. pastoris
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06913
Species: Human
Expression System: HEK293
BTLA Protein, Human, Recombinant (hFc)
TMPY-00175
Species: Human
Expression System: HEK293
BTLA Protein, Human, Recombinant (isoform1, His)
TMPY-06922
Species: Human
Expression System: HEK293
CTLA-4 Protein, Human, Recombinant (Flag)
TMPJ-00107
Species: Human
Expression System: Human Cells
MD2/LY96 Protein, Mouse, Recombinant (hFc)
TMPY-03999
Species: Mouse
Expression System: HEK293
LAG-3 Protein, Human, Recombinant (hFc)
TMPY-04528
Species: Human
Expression System: HEK293
BTLA Protein, Human, Recombinant (isoform 1,mFc)
TMPY-06829
Species: Human
Expression System: HEK293
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06931
Species: Human
Expression System: HEK293
LAG-3 Protein, Human, Recombinant (mFc)
TMPY-04731
Species: Human
Expression System: HEK293
BTLA Protein, Human, Recombinant (isoform1,hFc)
TMPY-06930
Species: Human
Expression System: HEK293
BTLA Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-05416
Species: Human
Expression System: HEK293
BTLA Protein, Human, Recombinant (mFc)
TMPY-05828
Species: Human
Expression System: HEK293
CD19 Protein, Rhesus macaque, Recombinant (hFc)
TMPJ-00329
Species: Rhesus macaque
Expression System: Human Cells
LAG-3 Protein, Mouse, Recombinant (hFc)
TMPY-04611
Species: Mouse
Expression System: HEK293
Cat No. Product Name
L2170 Immuno-Oncology Compound Library

454 compounds
A unique collection of 454 compounds acting on immune-oncology therapeutic targets can be used for high throughput and high content screening;
TargetMol