lovastatin

Lovastatin (MK-803) is an HMG-CoA reductase inhibitor (IC50=3.4 nM). Lovastatin lowers cholesterol and is commonly used as a lipid-lowering agent in the treatment of hypercholesterolemia.

Lovastatin Sodium is an HMG-CoA reductase inhibitor.

Keto lovastatin is an impurity of lovastatin with antibacterial properties. Lovastatin is a cell-permeable HMG-CoA reductase (HMG-CoA reductase) inhibitor used to reduce cholesterol levels.

Lovastatin-d3 is a deuterated compound of Lovastatin. Lovastatin has a CAS number of 75330-75-5. Lovastatin is an HMG-CoA Reductase Inhibitor, used for lowering cholesterol.

Lovastatin hydroxy acid sodium (Standard) is the standard substance of Lovastatin hydroxy acid sodium, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Lovastatin Sodium is an HMG-CoA reductase inhibitor.

Acetyllovastatin (acetate of Lovastatin) presents a moderate inhibitory effect against the acetylcholinesterase (IC50: 79 μg/mL). Lovastatin displays antifungal activity and suppresses the proliferation of a number of transformed cell lines.

Apomine (SR-9223i), an inhibitor of HMG-CoA-reductase, promotes apoptosis of myeloma cells in vitro and has been implicated in the regulation of myeloma in vivo. Apomine accelerates the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase and stimulates low-density lipoprotein receptor activity. Apomine enhances the antitumor effect of lovastatin on myeloma cells by downregulating 3-hydroxy-3-methylglutaryl-CoA reductase.

Monacolin J (Antibiotic MB 530A) is a cholesterol biosynthesis inhibitor.

Mevinolinic acid is an active metabolite of Lovastatin. Lovastatin is an HMG-CoA reductase inhibitor.

Dihydromevinolin is a potent cholesterol-lowering metabolite produced by Aspergillus terreus. It functions as an HMG-CoA reductase inhibitor.