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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T39905 | Legumain inhibitor 1 | Gamma-secretase | |
Legumain inhibitor 1 is a highly potent and specific Legumain inhibitor with potential anticancer activity for cancer research. | |||
T20626 | Esomeprazole | Proton pump , Cysteine Protease | |
Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis. Esomeprazole is a proton pump inhibitors (PPI). | |||
T12769 | RR-11a | Others | |
RR-11a is a synthetic enzyme Legumain inhibitor. | |||
T38984 | Z-Ala-Ala-Asn-AMC | Cbz-Ala-Ala-Asn-AMC,Z-Ala-Ala-Asn-AMC | |
Z-Ala-Ala-Asn-AMC, also known as Cbz-Ala-Ala-Asn-AMC, serves as a substrate for legumain. The overexpression of legumain in 293 HEK-Leg cells results in efficient cleavage of Cbz-Ala-Ala-Asn-AMC. | |||
T81945 | LE 28 | ||
LE 28 is a selective, activity-dependent probe for legumain that fluoresces exclusively upon binding to the active enzyme. It is applicable in research on cancers and inflammatory diseases [1]. | |||
T36903 | Rasagiline-13C3 (mesylate) | Rasagiline-13C3 (mesylate) | |
Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is se... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00876 | Legumain Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
The Mammalian Legumain, also known as LGMN, also called asparaginyl endopeptidase (AEP), is a cysteine protease belonging to peptidase family C13 with strict specificity for hydrolysis of asparaginyl bonds. Known previou... | |||
TMPY-02873 | Legumain Protein, Sus scrofa (Pig), Recombinant (His) | Sus scrofa (Pig) | HEK293 |
The Mammalian Legumain, also known as LGMN, also called asparaginyl endopeptidase (AEP), is a cysteine protease belonging to peptidase family C13 with strict specificity for hydrolysis of asparaginyl bonds. Known previou... | |||
TMPY-06640 | Legumain Protein, Human, Recombinant (His) | Human | HEK293 |
The Mammalian Legumain, also known as LGMN, also called asparaginyl endopeptidase (AEP), is a cysteine protease belonging to peptidase family C13 with strict specificity for hydrolysis of asparaginyl bonds. Known previou... | |||
TMPH-02432 | Legumain Protein, Cynomolgus, Recombinant (E. coli, His & Myc) | Cynomolgus | E. coli |
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Requir... | |||
TMPH-02431 | Legumain Protein, Cynomolgus, Recombinant (His & Myc) | Cynomolgus | Baculovirus |
Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Required for normal lysosomal protein degradation in renal proximal tubules. Requir... | |||
TMPK-01146 | LGMN Protein, Human, Recombinant (His) | Human | HEK293 |
Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in th... | |||
TMPY-00729 | Cystatin D Protein, Human, Recombinant (His) | Human | HEK293 |
Cystatins are natural inhibitors of papain-like (family C1) and legumain-related (family C13) cysteine peptidases. The mammalian cystatin superfamily members are of three major types, including the type 1 cystatins (stef... | |||
TMPY-02077 | Cystatin A Protein, Human, Recombinant (His) | Human | E. coli |
Cystatin-A, also known as Cystatin-AS, Stefin-A and CSTA, is a cytoplasm protein which belongs to thecystatin family. Cystatin-A / CSTA is a cysteine proteinase inhibitor with a molecular mass of 11 kDa, and is locate... | |||
TMPY-02090 | Cystatin B Protein, Human, Recombinant (His) | Human | E. coli |
Cystatin-B, also known as CPI-B, Liver thiol proteinase inhibitor, Stefin-B, CSTB and CST6, is a cytoplasm and nucleus protein which belongs to thecystatin family. Cystatin-B / CSTB is an intracellular thiol proteinas... |