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By Target- Potassium Channel
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Results for "
kv7.2 (kcnq2) channels
" in TargetMol Product Catalog- Inhibitors & Agonists5
ZTZ-240, ZTZ 240
T29236325457-98-5In house
ZTZ240 is a KCNQ2 channel activator used in the study of epilepsy.
- $293
Size
QTY
CitedXE 991 dihydrochloride
T17262122955-13-9
XE 991 dihydrochloride is a Kv7 (KCNQ) channel blocker. XE 991 dihydrochloride potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current (IC50s: 0.75 μM, 0.71 μM, 0.6 μM, and 0.98 μM, respectively).
- $41
Size
QTY
ML213
CID-3111211
T4030489402-47-3
ML213 (CID-3111211) is a selective activator of Kv7.2 (KCNQ2) and Kv7.4 (KCNQ4) channels, enhances Kv7.2 and Kv7.4 channels with EC50s of 230 and 510 nM, respectively.
- $34
Size
QTY
XE991 Cited
T78570122955-42-4In house
XE991 is a novel and selective Kv7 (KCNQ) channel blocker.XE 991 dihydrochloride inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channels, and M-current, and can be used for the study of neurological diseases.
- $35
Size
QTY
CitedKv7.2/Kv7.3 agonist 1
T2010632315450-35-0
Kv7.2/Kv7.3 agonist 1 (Compound 16) is an orally effective agonist for the KV7.2/7.3 channels (KV7.2/7.3 channel/KCNQ2/3) with an EC50 of 1.03 μM. This compound demonstrates analgesic effects in mouse models of chronic constriction injury (CCI) and Streptozotocin-induced diabetic peripheral neuropathy (DPNP), with ED50 values of 12.02 mg/kg and 9.63 mg/kg, respectively.
- $1,520
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QTY
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