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  • Histone Demethylase
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  • Histone Methyltransferase
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jarid1

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
KDM5-C70
T156481596348-32-1
KDM5-C70 is an ethyl ester derivative of KDM5-C49 and functions as an effective, cell-permeable, pan-KDM5 histone demethylase inhibitor. It exhibits an antiproliferative effect in myeloma cells and induces a genome-wide elevation of H3K4me3 levels.
  • $37
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PBIT
T164352514-30-9
PBIT inhibits JARID1B histone demethylase (IC50 of about 3 μM). PBIT also inhibits JARID1A and JARID1C (IC50s of 6 μM and 4.9 μM, respectively). PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes .
  • $34
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GSK467
T54841628332-52-4
GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).
  • $63
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