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(2)
By Target- JAK
- Antiviral(1)
- Apoptosis(1)
- Others(3)
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Results for "
jak in 10
" in TargetMol Product Catalog- Inhibitors & Agonists4
- Compound Libraries1
- Recombinant Protein6
- Isotope Products1
(R)-JAK2/STAT3-IN-10a
T72754L2485758-49-2In house
(R)-JAK2/STAT3-IN-10a is the R-isomer of JAK2/STAT3-IN-1.JAK2/STAT3-IN-1 is a GP130 D1 structural domain inhibitor with antitumor activity that inhibits the phosphorylation of JAK2 and STAT3. The KD value of (R)-JAK2/STAT3-IN-1 on GP130 protein is 3.8 μM.
- $195
Size
QTY
JAK2-IN-10
T882973035735-18-0
JAK2-IN-10 (compound 5) is a potent inhibitor of JAK2v617f, with an IC50 value of ≤10 nM.
- $9,710
Size
QTY
BVB808
NVP_BVB808
T891801414587-22-6
BVB808 (NVP_BVB808) is a selective inhibitor of JAK2, exhibiting approximately 10 times greater selectivity for JAK2 compared to other members of the JAK family (such as JAK1, JAK3, or TYK2) in vitro. By inhibiting the activation of JAK2, BVB808 reduces the phosphorylation of STAT5, thereby blocking the cell proliferation and survival signaling pathways that depend on JAK2. This compound is utilized in cancer research.
- $1,520
Size
QTY
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