indol-1

4-Methyl-2,3-dihydrocyclopenta[b]indol-1(4H)-one (4-Methyl-3,4-dihydro-2h-cyclopenta[b]indol-1-one) serves as a pharmaceutical intermediate for the synthesis of various active compounds.

1H-Isoindol-1-one,6-fluoro-2,3-dihydro-(9CI), with CAS No. 340702-10-5, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1H-Isoindol-1-one,6-fluoro-2,3-dihydro-(9CI) provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

(R)-1-[5-Amino-2-(2-benzyloxy-1,1-dimethyl-ethyl)-6-fluoro-indol-1-yl]-3-benzyloxy-propan-2-ol (VX-661 intermediate) is a pharmaceutical intermediate used in the synthesis of various active compounds.

Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM. It plays a central role in purine catabolism through the degradation of bioactive nucleotides facilitated by nucleic acid and nucleotide intermediates.

A2AR-agonist-1 (N-(2-(1H-Indol-3-yl)ethyl)adenosine) is a potent A2AR and ENT1 agonist (Ki: 4.39 and 3.47 for A2AR and ENT1. It targets the Adenosine A2A Receptor and Adenosine Transporter for Neuroprotection.

2-(1H-Indol-3-yl)ethan-1-ol (3-(2-Hydroxyethyl)indole) is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.

2-(5,7-dichloro-1H-indol-3-yl)ethan-1-amine is an indoleamine compound that is structurally similar to serotonin. It is a selective agonist at the 5-HT2A receptor and has potential applications in neuroscience.

1-benzyl-2-ethyl-4,5,6,7-tetrahydro-1H-indol-4-one is an inhibitor Bromodomain-containing protein 4 (human).

SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2)

1-Benzyl-I3C is an NEDD4-1 inhibitor.

BMS-265246 is a potent and selective CDK1/2 inhibitor. Its chemical name is (4-[R-(2,3-Dihydro-benzo[1,4]dioxin-6-yl)-1H-indol-1-yl]-1H-pyrazolo[3,4-d] pyrimidine-6-amine), and it functions by targeting CDK1 and CDK2 to potentially disrupt cell cycle progression.

VUF10460, a non-imidazole histamine H4 receptor agonist, [58C8-51-20-3] is structurally classified under the chlorobenzylpiperazine ethers with the IUPAC designation (2-[(2-chlorophenyl)methyl]-1-piperazinyl)(1H-indol-3-yl)methanone. It is typically utilized in pharmacological research and exhibits specificity for the H4 subtype, making it a valuable tool in immunological studies.

PEO-IAA (2-(1H-Indol-3-yl)-4-oxo-4-phenyl-butyric acid) is a novel potent auxin antagonist.

2-(5-(3-(5-Carboxypentyl)-1,1-dimethyl-1,3-dihydro-2H-benzo[e]indol-2-ylidene)penta-1,3-dien-1-yl)-1,1,3-trimethyl-1H-benzo[e]indol-3-ium is a useful organic compound for research related to life sciences and the catalog number is T64625.

3-(2-(7-(3-(2-Carboxyethyl)-1,1-dimethyl-1H-benzo[e]indol-3-ium-2-yl)hepta-2,4,6-trien-1-ylidene)-1,1-dimethyl-1,2-dihydro-3H-benzo[e]indol-3-yl)propanoate is a useful organic compound for research related to life sciences and the catalog number is T64779.

N-(5-((4-(1-Methyl-1H-indol-3-yl)pyridin-2-yl)amino)-2-(2-methylpyrrolidin-1-yl)phenyl)acrylamide is a useful organic compound for research related to life sciences and the catalog number is T64829.

N-(5-((4-(1-Methyl-1H-indol-3-yl)pyridin-2-yl)amino)-2-(piperidin-1-yl)phenyl)acrylamide is a useful organic compound for research related to life sciences and the catalog number is T64835.

1-(5-Bromo-1H-indol-3-yl)-N,N-dimethylmethanamine is a useful organic compound for research related to life sciences. The catalog number is T64897 and the CAS number is 830-93-3.

Methyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate is a useful organic compound for research related to life sciences. The catalog number is T65290 and the CAS number is 1601-18-9.

1,3-Dihydro-1-(piperidin-4-yl)(2H)indol-2-one is a useful organic compound for research related to life sciences. The catalog number is T66455 and the CAS number is 16223-25-9.

N1-Methyl-N4-[2-methyl-5-[[[1-methyl-3-(1-methyl-1H-indol-2-yl)-1H-indazol-5-yl]carbonyl]amino]phenyl]-1,4-benzenedicarboxamide (ACI) showed high affinity in BD2 DEC-Tec assay with an IC50 value of 13 nM.

WAY-658675, an active molecule, is a [4-amino-3-(4-pyridinyl)-4,5-dihydro-[3H]-pyrimido[5,4-b]indol-2-yl]-(1-piperidinyl)-methanone, known for its potent pharmacological properties.

3,3'-Bi[1H-indole] (3,3'-Biindole) is a marine derived natural products found in Nocardiopsis sp.

N-Boc-indole-2-boronic acid is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.