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Search Results for " ileum "

20

Compounds

Cat No. Product Name Synonyms Targets
T11428 Glyco-Obeticholic acid FXR
Glyco-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an agonist of the farnesoid X receptor (FXR).
T13092 Tauro-Obeticholic acid FXR
Tauro-Obeticholic acid is an active Obeticholic acid metabolite. Obeticholic acid is an orally bioavailable agonist of farnesoid-X receptor (FXR).
T14326 AS-35 Others
AS-35 is an orally effective, potent and selective antagonist of leukotrienes, antagonizes LTC4-, LTD4 and LTE4-induced contractions of the ileum. With IC50 values of 8 nM, 4 nM and 3 nM, respectively. It has antiallergi...
TP1819L Substance P 1-9 aceate Neurotensin Receptor
Substance P 1-9 aceate is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder.
T3A2467 Allocryptopine Thalictrimine,Fagarine I Potassium Channel
Allocryptopine (Thalictrimine) induces muscle contraction and relaxation in urinary bladder and ileum, respectively.
T3S2259 Methyl eugenol 4-allylveratrole,eugenyl methyl ether,O-methyleugenol,Eugenol Methyl ether GABA Receptor
1. Methyl eugenol (4-allylveratrole) is a natural constituent of the essential oils of a number of plants widely used in foodstuffs as flavouring agents, in view of the carcinogenic potential of ME, the need to check its...
T33449 ML 1035 ML103,ML-1035
ML 1035 is a benzamide that elicits contractions from guinea-pig non-stimulated ileum.
T12756 ROS 234 dioxalate Histamine Receptor
ROS 234 dioxalate is a potent antagonist of H3(pKB of 9.46 for Guinea-pig ileum H3-receptor)
T23829 Btm 1042 Btm1042,Btm-1042
Btm 1042 is an antispasmodic drug. It has been found to depress twitch responses in the ileum of guinea pigs.
T70688 S 0960
S 0960 is a dimeric bile acid analogue that acts as a specific inhibitor of the apical sodium-dependent bile salt transporter (ASBT) in the ileum.
TN4812 Pluviatolide AChR
(-)-Pluviatolide can inhibit electrically-induced and acetylcholine-induced contraction in the isolated guinea-pig ileum.
TN4713 Onitisin 5-HT Receptor
Onitisin, onitinoside and onitin can inhibit the contraction of isolated guinea-pig ileum.
T27140 Delequamine HCl RS-15385,RS15385,RS 15385,Delequamine,RS-15385-197
Delequamine HCl is a potent and selective alpha 2-adrenoceptor antagonist. Delequamine HCl has a pKi of 9.45 for alpha 2-adrenoceptors in the rat cortex (pA2 in the guinea-pig ileum of 9.72).
T37494 11-trans Leukotriene E4 11-trans Leukotriene E4
Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.
T69126 Clofeverine (free base)
Clofeverine (free base) is a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of clofeverine for spontaneous motility was com...
T71935 WIN 66306
WIN 66306 is a cyclic heptapeptide antagonist of neurokinin-1 (NK1) and NK2 receptors originally isolated from A. flavipes. It binds to NK1 and NK2 receptors and inhibits contractions induced by substance P in isolated g...
T8437 3-(4-prop-2-en-1-ylpiperazin-1-yl)quinox Others
3-(4-prop-2-en-1-ylpiperazin-1-yl)quinox Antagonism to 2-methyl-5-HT induced contractions in guinea pig ileum
T69324 Clofeverine hydrochloride
Clofeverine hydrochloride is the salt form of Clofeverine (free base), a highly selective relaxant for gastrointestinal smooth muscles with a beta-receptor stimulative nature. On isolated ileum, the inhibitory effect of ...
T37492 11-trans Leukotriene C4 11-trans Leukotriene C4
11-trans Leukotriene C4 (11-trans LTC4) is a C-11 double bond isomer of LTC4. LTC4 undergoes slow temperature-dependent isomerization to 11-trans LTC4 during storage. 11-trans LTC4 is produced in smaller amounts relative...
TP2075 Bombinakinin M
Potent bradykinin receptor agonist. Highly selective for mammalian arterial smooth muscle bradykinin receptors, displaying ~ 50-fold greater potency than bradykinin. Elicits dose-dependent contractile effects in smooth m...
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TargetMol