heterocycle

CL097 is an effective agonist of TLR7 and TLR8. CL097 induces pro-inflammatory cytokines in macrophages and NADPH oxidase priming, thereby increasing the fMLF-stimulated ROS production.

Clomazone (Magister) is an agricultural herbicide. The molecule consists of a 2-chlorobenzyl group bound to an N-O heterocycle called Isoxazole. Clomazone suppresses the biosynthesis of chlorophyll and other plant pigments.

Thianthrene (Dibenzodithiodioxane) is a sulfur-containing heterocyclic chemical compound that is a derivative of the parent heterocycle called dithiin and is easy to oxidize.

2,2':5',2''-Terthiophene (Trithiophene) (α-Terthiophene) is an oligomer of the heterocyclic compound thiophene, used as a building block for the organic semiconductor polythiophene.

DDCPPB-Glu is a 6-5 fused ring heterocycle antifolate that shows antitumor activity.

Celecoxib carboxylic acid acyl-β-D-glucuronide is a phase II metabolite of celecoxib . Celecoxib is an anti-inflammatory compound from the diaryl heterocycle class that selectively inhibits cyclooxygenase-2 (COX-2; IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). Celecoxib carboxylic acid acyl-β-D-glucuronide is a minor metabolite, accounting for 2% of the administered dose in human urine and rat bile.

Spinacine has been isolated from spinach and the roots of Panax ginseng. This conformationally constrained amino acid is a structural element in certain biologically active compounds as glucagon antagonists and angiotensin II receptor antagonists. Spinacine can be inserted as a His replacement with a locked imidazole moiety for elucidating the role of the lateral heterocycle in the activity of a peptide.

SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.

Compound 1059182-21-6 features a cyclic structure characterized by a nitrogen atom occupying an apex (corner) within the heterocycle. Its molecular scaffold integrates aromatic properties due to the presence of a conjugated system, while the inclusion of hydroxyl (-OH) groups confers reactive potential for subsequent modification. Additionally, a halogenated component, specifically a bromine atom, is attached to the aromatic ring, enhancing its propensity for undergoing further synthetic transformations.

Other heterocycle, fine chemical, catalyst

Heterocyclic Compound - Other heterocycle; Intermediate - Electrophile; Fine Chemicals