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SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.

L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).

HEAT hydrochloride is an α1-adrenoceptor antagonist.

Heat shock protein (Hsp) inhibitor II is the active form of Hsp inhibitor I and a benzylidene lactam compound that prevents the synthesis of inducible Hsps, such as Hsp105, Hsp72, and Hsp40. Hsp inhibitor II decreases Hsp72 synthesis in vivo and reduces thermotolerance of tumors in SCC VII tumor-containing mice. At 100 μM, it inhibits the development of thermotolerance in COLO 320 DM cells. Inhibition of Hsp70 with Hsp inhibitor II in combination with amphotericin B increases susceptibility of AmB-susceptible (MICs = 0.058 versus 0.27 μg/ml for combined and AmB alone, respectively) and AmB-resistant (MICs = 21.33 versus >32 μg/ml for combined and AmB alone, respectively) strains of A. fumigatus.

Phosphatidylinositols, comprising about 10% of total cellular phospholipids, are glycerophospholipids featuring a glycerol backbone, two non-polar fatty acid tails (primarily C16:0 and C18:0), and a polar inositol head group. Synthesized from cytidine diphosphate diacylglycerol (CPD-DAG) and myoinositol via phosphoinositol synthase, these compounds play pivotal roles in cellular processes, including calcium regulation, vesicle trafficking, mitogenesis, cell survival, and actin rearrangement. Phosphorylation of their inositol rings produces phosphoinositides, crucial for these cellular functions. [Matreya, LLC. Catalog No. 1048]

Gluten, Wheat, a visco-elastic and cohesive proteinaceous substance, is derived from wheat. It is known for its ability to induce celiac disease [1].

Succinylated Wheat Germ Agglutinin (Fluorescein) is a plant-derived lectin that can specifically interact with biomolecules such as polysaccharides and peptides, and is therefore used as a probe tool in biological analysis. Succinylated Wheat Germ Agglutinin (Fluorescein) is also a substance that can be used as a biomaterial or organic compound in life science research.

Wheat Germ Agglutinin (Peroxidase) is a plant-derived lectin that can specifically interact with biomolecules such as polysaccharides and peptides, and is therefore used as a probe tool in biological analysis.Wheat Germ Agglutinin (Peroxidase) is also a substance that can be used as a biomaterial or organic compound in life science research.

Wheat Germ Agglutinin (Rhodamine) is a plant-derived lectin that can specifically interact with biomolecules such as polysaccharides and peptides, and is therefore used as a probe tool in biological analysis.Wheat Germ Agglutinin (Rhodamine) is also a substance that can be used as a biomaterial or organic compound in life science research.

Succinylated Wheat Germ Agglutinin (Agarose) is a plant-derived lectin that can specifically interact with biomolecules such as polysaccharides and peptides, and is therefore used as a probe tool in biological analysis. Succinylated Wheat Germ Agglutinin (Agarose) is also a substance that can be used as a biomaterial or organic compound in life science research.

Wheat Germ Agglutinin (Agarose) is a plant-derived lectin that can specifically interact with biomolecules such as polysaccharides and peptides, and is therefore used as a probe tool in biological analysis. Wheat Germ Agglutinin (Agarose) is also a substance that can be used as a biomaterial or organic compound in life science research.

Succinylated Wheat Germ Agglutinin (Biotinylated) is a plant-derived lectin that can specifically interact with biomolecules such as polysaccharides and peptides, and is therefore used as a probe tool in biological analysis. Succinylated Wheat Germ Agglutinin (Biotinylated) is also a substance that can be used as a biomaterial or organic compound in life science research.

Wheat Germ Agglutinin (Biotinylated) is a plant-derived lectin that can specifically interact with biomolecules such as polysaccharides and peptides, and is therefore used as a probe tool in biological analysis. Wheat Germ Agglutinin (Biotinylated) is also a substance that can be used as a biomaterial or organic compound in life science research.

Wheat Germ Agglutinin (WGA) is a plant lectin that serves as a probe with specific binding affinity for biomolecules such as polysaccharides and polypeptides. WGA can be utilized as a biomaterial or organic compound relevant to life science research.

Wheat Germ Agglutinin (WGA) Fluorescein is a plant lectin that specifically binds to biomolecules such as polysaccharides and polypeptides, serving as a probe. It can be used as a biomaterial or organic compound in life sciences research.

Wheat germ oil is a nutritionally valuable oil notable for its high vitamin E content. It is rich in health-promoting bioactive compounds such as phytosterols, tocopherols, carotenoids, and omega-3 fatty acids.

Quercetin, a flavonoid natural product, is a SIRT1 activator. It is also a PI3K inhibitor, inhibiting PI3Kγ, PI3Kδ, and PI3Kβ with IC50 values of 2.4, 3.0, and 5.4 μM, respectively. Recognized as a heat shock protein inhibitor, Quercetin can significantly reduce exosome release in TII models by downregulating Hsp70 or Hsp90.

Apoptozole (Apoptosis Activator VII) inhibits the ATPase domain of Hsc70 and Hsp70, inducing apoptosis.

TRC051384 is a heat shock protein 70 (HSP70) inducer that reduces stroke-associated neuronal damage and increases survival in a rat model of transient ischemic stroke, activates heat shock factor-1 and leads to elevated molecular chaperone and anti-inflammatory activity, and enhances Hsp72 expression in neurons and glial cells.

ML346 is a novel activator of Hsp70.

Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.

VER-155008 is a potent Hsp70 family inhibitor with IC50 of 0.5 μM, 2.6 μM, and 2.6 μM in cell-free assays for HSP70, HSC70, and GRP78, respectively, >100-fold selectivity over HSP90.

Proteinase K (Protease K) is a non-specific serine protease that can tolerate changes in SDS, urea, pH (4-12), salt concentration, and temperature. Proteinase K hydrolyzes a wide range of peptide bonds and is used for protein digestion.

Debio 0932 (CUDC-305) is a heat shock protein 90 (Hsp90) inhibitor that targets the n-terminal atp-binding pocket to promote apoptosis, and has the advantage of being orally available and able to cross the blood-brain barrier (BBB) for the treatment of cancers such as non-small-cell lung cancer (NSCLC) and neuroblastoma.